Article Figures & Data
Figures
- Fig 1.
Flow chart of the study.
- Fig 2.
Distribution of modified Rankin Scale scores at 90 days according to successful reperfusion status.
Tables
- Table 1:
Baseline characteristics, procedure details, and complications according to reperfusion statusa
Successful Reperfusion Status P Value (mTICI 2b) Complete (mTICI 3) No. of patients 109 113 Age (mean) (yr) 69.0 ± 15.9 68.9 ± 14.7 .95 Men 41 (37.6) 55 (48.7) .096 Medical history Hypertension 63 (57.8) 70 (62.0) .53 Diabetes 18 (16.5) 21 (18.6) .69 Dyslipidemia 32 (29.4) 37 (32.7) .59 Current smokingb 20 (20.0) 22 (20.4) .95 NIHSS score (mean) 14.6 ± 6.3 13.7 ± 6.7 .30 Prestroke mRS ≥1 11 (10.1) 12 (10.6) .90 ASPECTS (median) (IQR) 8 (7–8) 8 (7–9) .32 Occlusion site ICA 27 (24.8) 18 (15.9) .18 MCA-M1 66 (60.5) 81 (71.7) MCA-M2 16 (14.7) 14 (12.4) TICI initial (1 vs 0) 10 (9.2) 9 (8.0) .75 Favorable collateral flowc 79 (77.5) 97 (91.5) .005 Etiology Cardioembolism 73 (67.0) 64 (56.7) .020 Large-artery atherosclerosis 5 (4.6) 18 (15.9) Other or undetermined 31 (28.4) 31 (27.4) Previous use of IV thrombolysis 77 (70.6) 73 (64.6) .34 General anesthesia 36 (33.0) 34 (30.1) .64 Onset to reperfusion time (median) (IQR) (min) 310 (260–361) 285 (225–340) .021 Onset-to-groin puncture 251 (208–300) 237 (191–292) .11 Groin puncture to reperfusion (median) (IQR) (min) 50 (31–68) 40 (24–58) .018 Total number of passes (median) (IQR) 2 (1–3) 1 (1–2) .0002 Periprocedural complication 13 (11.9) 9 (8.0) .32 Adjunctive treatment 7 (6.4) 3 (2.7) .21 mTICI 2b (n = 109) Complete (mTICI 3) (n = 113) OR (95% CI) P OR (95% CI)b Pb Excellent outcome 42 (38.5) 67 (59.3) 2.32 (1.35–3.98) .002 2.98 (1.46–6.06) .0037 Favorable outcome 55 (50.5) 81 (71.7) 2.49 (1.42–4.33) .001 3.34 (1.56–7.11) .002 90-Day mortality 18 (16.5) 10 (8.9) 0.49 (0.21–1.12) .086 NR NR Any ICH 49 (45.0) 26 (23.0) 0.37 (0.20–0.65) <.001 0.33 (0.16–0.64) .001 HI1 22 (20.2) 20 (17.7) – – – – HI2 17 (15.6) 4 (3.5) – – – – PH1 4 (3.7) 1 (0.9) – – – – PH2 6 (5.5) 1 (0.9) – – – – Note:—NR indicates not reportable regarding the small number of events; OR, odds ratio.
↵a Excellent outcome was defined as 90-day mRS ≤ 1, and favorable outcome, as 90-day mRS ≤ 2. ORs were calculated using mTICI 2b reperfusion as a reference.
↵b Adjusted on center, age, diabetes, admission NIHSS score, prior use of IV thrombolysis, site of occlusion, favorable collateral flow, etiology, and onset to reperfusion time using multivariable logistic regression models (after a mean of 10 imputations to handle missing data on favorable collateral flow).
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