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Research ArticleNeurointervention

Stent Retriever Thrombectomy in Patients Who Are Ineligible for Intravenous Thrombolysis: A Multicenter Retrospective Observational Study

F. Dorn, S. Prothmann, M. Patzig, H. Lockau, C. Kabbasch, O. Nikoubashman, T. Liebig, C. Zimmer, H. Brückmann, M. Wiesmann, H. Stetefeld, H. Poppert, A. Reich, L. Kellert and G. Fesl
American Journal of Neuroradiology February 2016, 37 (2) 305-310; DOI: https://doi.org/10.3174/ajnr.A4520
F. Dorn
aFrom the Departments of Neuroradiology and Radiology (F.D., H.L., C.K., T.L.)
eDepartments of Neuroradiology (F.D., M.P., H.B., G.F.)
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  • ORCID record for F. Dorn
S. Prothmann
cDepartments of Neuroradiology (S.P., C.Z.)
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M. Patzig
eDepartments of Neuroradiology (F.D., M.P., H.B., G.F.)
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H. Lockau
aFrom the Departments of Neuroradiology and Radiology (F.D., H.L., C.K., T.L.)
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  • ORCID record for H. Lockau
C. Kabbasch
aFrom the Departments of Neuroradiology and Radiology (F.D., H.L., C.K., T.L.)
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  • ORCID record for C. Kabbasch
O. Nikoubashman
gDepartments of Neuroradiology (O.N., M.W.)
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  • ORCID record for O. Nikoubashman
T. Liebig
aFrom the Departments of Neuroradiology and Radiology (F.D., H.L., C.K., T.L.)
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  • ORCID record for T. Liebig
C. Zimmer
cDepartments of Neuroradiology (S.P., C.Z.)
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H. Brückmann
eDepartments of Neuroradiology (F.D., M.P., H.B., G.F.)
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M. Wiesmann
gDepartments of Neuroradiology (O.N., M.W.)
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H. Stetefeld
bNeurology (H.S.), University Hospital of Cologne, Cologne, Germany
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H. Poppert
dNeurology (H.P.), Klinikum Rechts der Isar, Technical University, Munich, Germany
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A. Reich
hNeurology (A.R.), University Hospital of Aachen, Aachen, Germany.
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L. Kellert
fNeurology (L.K.), University Hospital of Munich, Munich, Germany
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G. Fesl
eDepartments of Neuroradiology (F.D., M.P., H.B., G.F.)
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Article Figures & Data

Tables

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    Table 1:

    Relevant patient data listed for all patientsa

    Patient Data
    No. of patients130
    Mean age (yr)68.8 (min. 18, max. 90)
    Sex
        Female64 (49.2%)
        Male66 (50.8%)
    Median NIHSS score on admission (range)16.32 ± 6.4 (min. 2, max. 34)
    Intracranial occlusion site
        Proximal ICA + distal ICA/MCA17 (13.1%)
        Terminus ICA25 (19.2%)
        M177 (59.2%)
        Main branch71 (54.6%)
        Postbifurcal segment6 (4.6%)
        M211 (8.5%)
    Reperfusion results
        TICI 05 (3.6%)
        TICI 14 (3.1%)
        TICI 2a22 (15.4%)
        TICI 2b46 (35.4%)
        TICI 355 (42.3%)
    Time from stroke onset to groin puncture (minutes) (mean)175.7 ± 45.4 (min. 65, max. 270)
    Time from stroke onset to final recanalization (minutes) (mean)246.0 ± 71.7 (min. 94, max. 432)
    mRS after 3 months (n = 124)
        017 (13.1%)
        112 (9.2%)
        218 (13.8%)
        317 (13.1%)
        416 (12.3%)
        514 (10.8%)
        630 (23.1%)
    Symptomatic hemorrhage17 Patients (13.1%)
    Periprocedural complications10 (7.7%)
        SAH6 (4.6%)
        Thrombus lost1 (0.8%)
        Dissection2 (1.6%)
        Loss of device2 (1.6%)
    • Note:—Max. indicates maximum; min, minimum.

    • ↵a Numbers of patients and percentage are displayed unless otherwise noted.

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    Table 2:

    Summary of contraindications against IV thrombolysis

    ContraindicationNo. of Patients (n = 130)
    Phenprocoumon (INR > 1.7)44 (33.8%)
    Recent surgery23 (17.7%)
    Recent stroke21 (16.2%)
    Emergency stentangioplasty10 (7.7%)
    IV heparin6 (4.6%)
    Metastasizing cancer5 (3.8%)
    History of ICH3 (2.3%)
    Previous trauma2 (1.5%)
    Epileptic onset2 (1.5%)
    Gastrointestinal bleeding2 (1.5%)
    Coagulative disorder1 (0.8%)
    Intracranial aneurysm1 (0.8%)
    Not evaluable10 (7.7%)
    • Note:—INR indicates international normalized ratio; ICH, intracerebral hemorrhage.

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American Journal of Neuroradiology: 37 (2)
American Journal of Neuroradiology
Vol. 37, Issue 2
1 Feb 2016
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F. Dorn, S. Prothmann, M. Patzig, H. Lockau, C. Kabbasch, O. Nikoubashman, T. Liebig, C. Zimmer, H. Brückmann, M. Wiesmann, H. Stetefeld, H. Poppert, A. Reich, L. Kellert, G. Fesl
Stent Retriever Thrombectomy in Patients Who Are Ineligible for Intravenous Thrombolysis: A Multicenter Retrospective Observational Study
American Journal of Neuroradiology Feb 2016, 37 (2) 305-310; DOI: 10.3174/ajnr.A4520

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Stent Retriever Thrombectomy in Patients Who Are Ineligible for Intravenous Thrombolysis: A Multicenter Retrospective Observational Study
F. Dorn, S. Prothmann, M. Patzig, H. Lockau, C. Kabbasch, O. Nikoubashman, T. Liebig, C. Zimmer, H. Brückmann, M. Wiesmann, H. Stetefeld, H. Poppert, A. Reich, L. Kellert, G. Fesl
American Journal of Neuroradiology Feb 2016, 37 (2) 305-310; DOI: 10.3174/ajnr.A4520
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