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Research ArticleHead and Neck Imaging

Imaging Features of Malignant Lacrimal Sac and Nasolacrimal Duct Tumors

V.A. Kumar, B. Esmaeli, S. Ahmed, B. Gogia, J.M. Debnam and L.E. Ginsberg
American Journal of Neuroradiology November 2016, 37 (11) 2134-2137; DOI: https://doi.org/10.3174/ajnr.A4882
V.A. Kumar
aFrom the Department of Diagnostic Radiology (V.A.K., S.A., B.G., J.M.D, L.E.G.)
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B. Esmaeli
bOrbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery (B.E.), University of Texas MD Anderson Cancer Center, Houston, Texas.
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S. Ahmed
aFrom the Department of Diagnostic Radiology (V.A.K., S.A., B.G., J.M.D, L.E.G.)
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B. Gogia
aFrom the Department of Diagnostic Radiology (V.A.K., S.A., B.G., J.M.D, L.E.G.)
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J.M. Debnam
aFrom the Department of Diagnostic Radiology (V.A.K., S.A., B.G., J.M.D, L.E.G.)
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L.E. Ginsberg
aFrom the Department of Diagnostic Radiology (V.A.K., S.A., B.G., J.M.D, L.E.G.)
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    Fig 1.

    Normal anatomy of the lacrimal drainage system apparatus, which includes the canaliculi, lacrimal sac, and nasolacrimal duct.

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    Fig 2.

    A 46-year-old woman with moderately differentiated invasive SCCA of the right lacrimal sac and nasolacrimal duct. Post-contrast-enhanced CT shows tumor extension from the lacrimal sac into the medial canthus region (arrow), which is a common site of tumor spread.

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    Fig 3.

    An 85-year-old man with metastatic melanoma to the lacrimal sac and nasolacrimal duct with extension into the medial canthus region. Axial MR imaging demonstrates an isointense mass in the right medial canthus on T1WI (A), isointensity on T2WI (B), and enhancement on postcontrast T1WI (C).

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    Fig 4.

    A 50-year-old man with adenocarcinoma of the left lacrimal sac and nasolacrimal duct. A, Postcontrast thin-section coronal CT reformatted images demonstrate tumor in the lacrimal sac and duct (white arrow) with direct extension into the inferior intraconal orbital space (black arrow). B, Due to the extent of tumor spread, the patient underwent left orbital exenteration, maxillectomy, and free flap reconstruction (white arrowheads) with adjuvant radiation therapy and has been disease-free for 3 years.

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    Fig 5.

    A 73-year-old woman with well-differentiated SCCA of the lacrimal sac and nasolacrimal duct. A, Post-contrast-enhanced CT demonstrates an enhancing tumor within the left lacrimal sac (arrow). B, At a slightly more inferior level (bone window), note the mild expansion of the lacrimal bony canal by tumor (arrow).

Tables

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  • Imaging features and regional spread of malignant lacrimal sac and nasolacrimal duct tumors

    FeaturesNo. of Patients
    Tumor location along lacrimal system on CT and MRI (n = 18)
        Lacrimal sac only3
        Nasolacrimal duct only0
        Involving lacrimal sac and nasolacrimal duct15
    Tumor involvement of the nasolacrimal duct bony canal on CT (n = 16)
        No duct dilation2
        Smoothly expanded duct11
        Erosive/lytic changes to duct2
        Iatrogenic changes to duct from prior dacryocystorhinostomy1
    Orbit involvement by tumor (n = 18)
        Medial cantus/extraconal space of orbit16
        Intraconal space of orbit2
    Sinonasal involvement by tumor in primary malignant tumors of the lacrimal sac or duct (n = 5)a
        Ethmoid sinus4
        Maxillary sinus3
        Nasal cavity5
    Other findings (n = 18)
        Nodal metastasis1
        Distant metastasis0
        Perineural tumor spread along the infraorbital nerve0
        Intracranial extension0
        Dacryocystocele formation0
    • ↵a Please note that some patients had >1 subsite of sinonasal tumor extension.

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American Journal of Neuroradiology: 37 (11)
American Journal of Neuroradiology
Vol. 37, Issue 11
1 Nov 2016
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Cite this article
V.A. Kumar, B. Esmaeli, S. Ahmed, B. Gogia, J.M. Debnam, L.E. Ginsberg
Imaging Features of Malignant Lacrimal Sac and Nasolacrimal Duct Tumors
American Journal of Neuroradiology Nov 2016, 37 (11) 2134-2137; DOI: 10.3174/ajnr.A4882

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Imaging Features of Malignant Lacrimal Sac and Nasolacrimal Duct Tumors
V.A. Kumar, B. Esmaeli, S. Ahmed, B. Gogia, J.M. Debnam, L.E. Ginsberg
American Journal of Neuroradiology Nov 2016, 37 (11) 2134-2137; DOI: 10.3174/ajnr.A4882
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