Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

M. Varosanec; T. Uher; D. Horakova; J. Hagemeier; N. Bergsland; M. Tyblova; Z. Seidl; M. Vaneckova; J. Krasensky; M.G. Dwyer; E. Havrdova; R. Zivadinov

doi:10.3174/ajnr.A4330

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Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

M. Varosanec, T. Uher, D. Horakova, J. Hagemeier, N. Bergsland, M. Tyblova, Z. Seidl, M. Vaneckova, J. Krasensky, M.G. Dwyer, E. Havrdova and R. Zivadinov

American Journal of Neuroradiology August 2015, 36 (8) 1457-1464; DOI: https://doi.org/10.3174/ajnr.A4330

M. Varosanec

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

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T. Uher

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

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D. Horakova

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

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J. Hagemeier

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

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N. Bergsland

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

dIRCCS “Santa Maria Nascente” (N.B.), Don Gnocchi Foundation, Milan, Italy.

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M. Tyblova

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

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Z. Seidl

cDepartment of Radiology (Z.S., M.V., J.K.), Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

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M. Vaneckova

cDepartment of Radiology (Z.S., M.V., J.K.), Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

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J. Krasensky

cDepartment of Radiology (Z.S., M.V., J.K.), Charles University in Prague, First Faculty of Medicine and General University Hospital, Prague, Czech Republic

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M.G. Dwyer

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

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E. Havrdova

bDepartment of Neurology and Center of Clinical Neuroscience (T.U., D.H., M.T., E.H.)

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R. Zivadinov

aFrom the Buffalo Neuroimaging Analysis Center (M.V., T.U., J.H., N.B., M.G.D., R.Z.), Department of Neurology, University at Buffalo SUNY, Buffalo, New York

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M. Varosanec, T. Uher, D. Horakova, J. Hagemeier, N. Bergsland, M. Tyblova, Z. Seidl, M. Vaneckova, J. Krasensky, M.G. Dwyer, E. Havrdova, R. Zivadinov

Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

American Journal of Neuroradiology Aug 2015, 36 (8) 1457-1464; DOI: 10.3174/ajnr.A4330

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Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome

M. Varosanec, T. Uher, D. Horakova, J. Hagemeier, N. Bergsland, M. Tyblova, Z. Seidl, M. Vaneckova, J. Krasensky, M.G. Dwyer, E. Havrdova, R. Zivadinov

American Journal of Neuroradiology Aug 2015, 36 (8) 1457-1464; DOI: 10.3174/ajnr.A4330

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