Article Figures & Data
Figures
- Fig 1.
Analysis of radial VIBE images provide maps of different permeability parameters: peak, area under the curve, time of maximum enhancement, wash-in, and washout.
- Fig 2.
GRASP images in a healthy volunteer show the ROIs in the anterior pituitary gland (A), posterior pituitary gland (B), and median eminence (C). Sagittal reference planes are shown top right. Corresponding signal-time curves from the ROIs (D) demonstrate a different pattern of enhancement in the anterior (red) and posterior pituitary gland (yellow) and the median eminence (light blue).
- Fig 3.
A, GRASP image demonstrates placement of ROIs within the normal-appearing pituitary gland and microadenoma. B, Corresponding signal-time curves are shown. Peak enhancement from the anterior pituitary gland is seen at approximately 80 seconds with subsequent gradual washout. Peak enhancement from the microadenoma is seen at approximately 100 seconds with a subsequent plateau. There is a significant difference in the enhancement between the anterior pituitary gland and the microadenoma from 60 seconds onward.
- Fig 4.
Signal-time curve derived from an ROI applied to a cyst demonstrates a flat STC compared with the normal STCs from the anterior pituitary gland, posterior pituitary gland, and median eminence evaluated in the same patient.
Tables
- Table 1:
Mean, SD, median, maximum, and lower and upper limits of a 95% confidence interval of the mean for the percentage change in the peak enhancement estimate from time T0 = 60 seconds to time T8 = 140 seconds in the normal-appearing anterior pituitary gland of group 2 patients
Time Mean SD Median Maximum Lower Upper 1 9.82 9.97 5.25 30.99 5.16 14.49 2 6.11 6.65 4.52 21.69 3.00 9.23 3 2.00 2.52 1.05 8.53 0.82 3.18 4 2.17 2.55 1.18 8.98 0.97 3.36 5 1.41 0.87 1.06 2.76 1.01 1.82 6 1.38 0.87 1.04 3.82 0.98 1.79 7 0.94 0.87 0.71 3.28 0.53 1.35 8 0.57 0.33 0.62 1.30 0.42 0.73 - Table 2:
Values of perfusion parameters obtained from ROI analysis in different regions of the normal-appearing pituitary glanda
Parameter Anterior Posterior Median Eminence Mean SD Mean SD Mean SD AUC 69980.65 20169.32 37500.10 17701.73 40246.39 16626.70 Peak 754.94 242.04 439.61 205.67 446.62 192.66 TME (sec) 86.55 19.23 58.96 16.23 62.60 18.70 Wash-in 10.92 3.89 9.14 4.20 8.54 3.71 Washout 1.52 1.34 1.90 1.48 1.56 1.27 Note:—TME indicates time of maximum enhancement.
↵a All parameters other than TME are dimensionless.
- Table 3:
Mean, minimum, and maximum peak enhancement values measured at different times in the microadenoma of group 2 patients
Time (sec) Mean PE Min PE Max PE 60 327 90 500 70 365 120 600 80 400 170 630 90 420 200 660 100 417 180 650 110 342 165 625 120 345 172 620 130 346 171 613 140 344 170 613 Note:—PE indicates peak enhancement; Min, minimum; Max, maximum.
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