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Research ArticleBrain

Contribution and Additional Impact of Imaging to the SPAN-100 Score

P. Krishnan, G. Saposnik, B. Ovbiagele, L. Zhang, S. Symons and R. Aviv
American Journal of Neuroradiology April 2015, 36 (4) 646-652; DOI: https://doi.org/10.3174/ajnr.A4195
P. Krishnan
aFrom the Division of Neuroradiology (P.K., S.S., R.A.), Department of Medical Imaging, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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G. Saposnik
bStroke Outcome Reach Center (G.S.), Division of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Ontario, Canada
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B. Ovbiagele
cDepartment of Neurosciences (B.O.), Medical University of South Carolina, Charleston, South Carolina
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L. Zhang
dBiostatistician (L.Z.), Sunnybrook Health Sciences Center, Toronto, Ontario, Canada.
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S. Symons
aFrom the Division of Neuroradiology (P.K., S.S., R.A.), Department of Medical Imaging, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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R. Aviv
aFrom the Division of Neuroradiology (P.K., S.S., R.A.), Department of Medical Imaging, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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REFERENCES

  1. 1.↵
    1. Rabinstein A.,
    2. Rundek T
    . Prediction of outcome after ischemic stroke: the value of clinical scores. Neurology 2013;80:15–16
    CrossRef
  2. 2.↵
    1. Weimar C,
    2. Konig IR,
    3. Kraywinkel K, et al
    . Age and National Institutes of Health Stroke Scale Score within 6 hours after onset are accurate predictors of outcome after cerebral ischemia: development and external validation of prognostic models. Stroke 2004;35:158–62
    Abstract/FREE Full Text
  3. 3.↵
    1. König I,
    2. Ziegler A,
    3. Bluhmki E, et al
    . Predicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trials. Stroke 2008;39:1821–26
    Abstract/FREE Full Text
  4. 4.↵
    1. Saposnik G,
    2. Guzik A,
    3. Reeves M, et al
    . SPAN 100: a practical method of stroke prognostication combining age and NIHSS after tPA. Neurology 2013;80:21–28
    CrossRef
  5. 5.↵
    1. Saposnik G,
    2. Cote R,
    3. Phillips S, et al
    . Stroke Outcome Research Canada (SORCan) Working Group: variables associated with 7-day, 30-day, and 1-year fatality after ischemic stroke. Stroke 2008;39:2522–30
    Abstract/FREE Full Text
  6. 6.↵
    1. Obach V,
    2. Oleaga L,
    3. Urra X, et al
    . Multimodal CT-assisted thrombolysis in patients with acute stroke: a cohort study. Stroke 2011;42:1129–31
    Abstract/FREE Full Text
  7. 7.↵
    1. Lev MH,
    2. Segal AZ,
    3. Farkas J, et al
    . Utility of perfusion-weighted CT imaging in acute middle cerebral artery stroke treated with intra-arterial thrombolysis: prediction of final infarct volume and clinical outcome. Stroke 2001;32:2021–18
    Abstract/FREE Full Text
  8. 8.↵
    1. Campbell BC,
    2. Weir L,
    3. Desmond PM, et al
    . CT perfusion improves diagnostic accuracy and confidence in acute ischaemic stroke. J Neurol Neurosurg Psychiatry 2013;84:613–18
    Abstract/FREE Full Text
  9. 9.↵
    1. Hopyan J,
    2. Ciarallo A,
    3. Dowlatshahi D, et al
    . Certainty of stroke diagnosis: incremental benefit with CT perfusion over noncontrast CT and CT angiography. Radiology 2010;255:142–53
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Demchuk A,
    2. Menon B,
    3. Goyal M
    . Imaging based selection in acute ischemic stroke trials: a quest for imaging sweet spots. Ann N Y Acad Sci 2012;1268:63–71
    CrossRefPubMed
  11. 11.↵
    1. Eilaghi A,
    2. d'Esterre CD,
    3. Lee TY, et al
    . Toward patient-tailored perfusion thresholds for prediction of stroke outcome. AJNR Am J Neuroradiol 2014;35:472–77
    Abstract/FREE Full Text
  12. 12.↵
    1. Tan IY,
    2. Demchuk AM,
    3. Hopyan J, et al
    . CT angiography clot burden score and collateral score: correlation with clinical and radiologic outcomes in acute middle cerebral artery infarct. AJNR Am J Neuroradiol 2009;30:525–31
    Abstract/FREE Full Text
  13. 13.↵
    1. Aviv RI,
    2. d'Esterre CD,
    3. Murphy BD, et al
    . Hemorrhagic transformation of ischemic stroke: prediction with CT perfusion. Radiology 2009;250:867–77
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Brozici M,
    2. van der Zwan A,
    3. Hillen B
    . Anatomy and functionality of leptomeningeal anastomoses: a review. Stroke 2003;34:2750–62
    Abstract/FREE Full Text
  15. 15.↵
    1. Souza L,
    2. Yoo A,
    3. Chaudhry Z, et al
    . Malignant CTA collateral profile is highly specific for large admission DWI infarct core and poor outcome in acute stroke. AJNR Am J Neuroradiol 2012;33:1331–36
    Abstract/FREE Full Text
  16. 16.↵
    1. Lima FO,
    2. Furie KL,
    3. Silva GS, et al
    . The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion. Stroke 2010;41:2316–22
    Abstract/FREE Full Text
  17. 17.↵
    1. Liebeskind D
    . Collateral perfusion: time for novel paradigms in cerebral ischemia. Int J Stroke 2012;7:309–10
    PubMedWeb of Science
  18. 18.↵
    1. Bang O,
    2. Saver J,
    3. Kim S, et al
    . Collateral flow averts hemorrhagic transformation after endovascular therapy for acute ischemic stroke. Stroke 2011;42:2235–39
    Abstract/FREE Full Text
  19. 19.↵
    1. Bhatt A,
    2. Vora A,
    3. Thomas A, et al
    . Lower pretreatment cerebral blood volume affects hemorrhagic risks after intra-arterial revascularization in acute stroke. Neurosurgery 2008;63:874–78; discussion 878–79
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Jain A,
    2. Jain M,
    3. Kanthala A, et al
    . Association of CT perfusion parameters with hemorrhagic transformation in acute ischemic stroke. AJNR Am J Neuroradiol 2013;34:1895–900
    Abstract/FREE Full Text
  21. 21.↵
    1. Dzialowski I,
    2. Hill MD,
    3. Coutts SB, et al
    . Extent of early ischemic changes on computed tomography (CT) before thrombolysis: prognostic value of the Alberta Stroke Program Early CT Score in ECASS II. Stroke 2006;37:973–78
    Abstract/FREE Full Text
  22. 22.↵
    1. Menon BK,
    2. Puetz V,
    3. Kochar P, et al
    . ASPECTS and other neuroimaging scores in the triage and prediction of outcome in acute stroke patients. Neuroimaging Clin N Am 2011;21:407–23, xii
    CrossRefPubMed
  23. 23.↵
    1. Vogt G,
    2. Laage R,
    3. Shuaib A, et al
    . Initial lesion volume is an independent predictor of clinical stroke outcome at day 90: an analysis of the Virtual International Stroke Trials Archive (VISTA) database. Stroke 2012;43:1266–72
    Abstract/FREE Full Text
  24. 24.↵
    1. Schiemanck SK,
    2. Kwakkel G,
    3. Post MW, et al
    . Predictive value of ischemic lesion volume assessed with magnetic resonance imaging for neurological deficits and functional outcome post stroke: a critical review of the literature. Neurorehabil Neural Repair 2006;20:492–502
    Abstract/FREE Full Text
  25. 25.↵
    1. Murphy A,
    2. Symons SP,
    3. Hopyan J, et al
    . Factors influencing clinically meaningful recanalization after IV-rtPA in acute ischemic stroke. AJNR Am J Neuroradiol 2013;34:146–52
    Abstract/FREE Full Text
  26. 26.↵
    1. Sillanpää N,
    2. Saarinen JT,
    3. Rusanen H, et al
    . Location of the clot and outcome of perfusion defects in acute anterior circulation stroke treated with intravenous thrombolysis. AJNR Am J Neuroradiol 2013;34:100–06
    Abstract/FREE Full Text
  27. 27.↵
    1. Puetz V,
    2. Dzialowski I,
    3. Hill MD, et al
    . Calgary CTA Study Group: intracranial thrombus extent predicts clinical outcome, final infarct size and hemorrhagic transformation in ischemic stroke: the clot burden score. Int J Stroke 2008;3:230–36
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Roberts HC,
    2. Roberts TP,
    3. Smith WS, et al
    . Multisection dynamic CT perfusion for acute cerebral ischemia: the “toggling-table” technique. AJNR Am J Neuroradiol 2001;22:1077–80
    Abstract/FREE Full Text
  29. 29.↵
    1. Youn SW,
    2. Kim JH,
    3. Weon YC, et al
    . Perfusion CT of the brain using 40-mm-wide detector and toggling table technique for initial imaging of acute stroke. AJR Am J Roentgenol 2008;191:W120–26
    CrossRefPubMed
  30. 30.↵
    1. Lev MH
    . Acute stroke imaging: what is sufficient for triage to endovascular therapies? AJNR Am J Neuroradiol 2012;33:790–92
    FREE Full Text
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American Journal of Neuroradiology: 36 (4)
American Journal of Neuroradiology
Vol. 36, Issue 4
1 Apr 2015
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P. Krishnan, G. Saposnik, B. Ovbiagele, L. Zhang, S. Symons, R. Aviv
Contribution and Additional Impact of Imaging to the SPAN-100 Score
American Journal of Neuroradiology Apr 2015, 36 (4) 646-652; DOI: 10.3174/ajnr.A4195

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Contribution and Additional Impact of Imaging to the SPAN-100 Score
P. Krishnan, G. Saposnik, B. Ovbiagele, L. Zhang, S. Symons, R. Aviv
American Journal of Neuroradiology Apr 2015, 36 (4) 646-652; DOI: 10.3174/ajnr.A4195
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