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Research ArticleBrain
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Subcortical Deep Gray Matter Pathology in Patients with Multiple Sclerosis Is Associated with White Matter Lesion Burden and Atrophy but Not with Cortical Atrophy: A Diffusion Tensor MRI Study

R. Cappellani, N. Bergsland, B. Weinstock-Guttman, C. Kennedy, E. Carl, D.P. Ramasamy, J. Hagemeier, M.G. Dwyer, F. Patti and R. Zivadinov
American Journal of Neuroradiology May 2014, 35 (5) 912-919; DOI: https://doi.org/10.3174/ajnr.A3788
R. Cappellani
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
cDepartment GF Ingrassia, Section of Neurosciences (R.C., F.P.), University of Catania, Catania, Italy.
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N. Bergsland
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
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B. Weinstock-Guttman
bJacobs Neurological Institute, Department of Neurology (B.W.-G., R.Z.), State University of New York, Buffalo, New York
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C. Kennedy
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
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E. Carl
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
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D.P. Ramasamy
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
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J. Hagemeier
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
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M.G. Dwyer
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
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F. Patti
cDepartment GF Ingrassia, Section of Neurosciences (R.C., F.P.), University of Catania, Catania, Italy.
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R. Zivadinov
aFrom the Buffalo Neuroimaging Analysis Center (R.C., N.B., C.K., E.C., D.P.R., J.H., M.G.D., R.Z.)
bJacobs Neurological Institute, Department of Neurology (B.W.-G., R.Z.), State University of New York, Buffalo, New York
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      Online Table 1: Brain regions and DTI measures of healthy control participants, patients with RRMS, and patients with PMS

      Online Table 2: Brain regions and DTI measures of healthy control participants, patients with RRMS, and patients with PMS
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American Journal of Neuroradiology: 35 (5)
American Journal of Neuroradiology
Vol. 35, Issue 5
1 May 2014
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R. Cappellani, N. Bergsland, B. Weinstock-Guttman, C. Kennedy, E. Carl, D.P. Ramasamy, J. Hagemeier, M.G. Dwyer, F. Patti, R. Zivadinov
Subcortical Deep Gray Matter Pathology in Patients with Multiple Sclerosis Is Associated with White Matter Lesion Burden and Atrophy but Not with Cortical Atrophy: A Diffusion Tensor MRI Study
American Journal of Neuroradiology May 2014, 35 (5) 912-919; DOI: 10.3174/ajnr.A3788

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Subcortical Deep Gray Matter Pathology in Patients with Multiple Sclerosis Is Associated with White Matter Lesion Burden and Atrophy but Not with Cortical Atrophy: A Diffusion Tensor MRI Study
R. Cappellani, N. Bergsland, B. Weinstock-Guttman, C. Kennedy, E. Carl, D.P. Ramasamy, J. Hagemeier, M.G. Dwyer, F. Patti, R. Zivadinov
American Journal of Neuroradiology May 2014, 35 (5) 912-919; DOI: 10.3174/ajnr.A3788
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Cited By...

  • Innate Immune Cell-Related Pathology in the Thalamus Signals a Risk for Disability Progression in Multiple Sclerosis
  • Functional Brain Networks Are Altered in Type 2 Diabetes and Prediabetes: Signs for Compensation of Cognitive Decrements? The Maastricht Study
  • Longitudinal Mixed-Effect Model Analysis of the Association between Global and Tissue-Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome
  • Modeling the Relationship among Gray Matter Atrophy, Abnormalities in Connecting White Matter, and Cognitive Performance in Early Multiple Sclerosis
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