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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Safety and Effectiveness of Sacroplasty: A Large Single-Center Experience

A.C. Gupta, R.V. Chandra, A.J. Yoo, T.M. Leslie-Mazwi, D.L. Bell, B.P. Mehta, T.L. Vanderboom, J.D. Rabinov, M. Larvie and J.A. Hirsch
American Journal of Neuroradiology November 2014, 35 (11) 2202-2206; DOI: https://doi.org/10.3174/ajnr.A4027
A.C. Gupta
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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R.V. Chandra
bDepartment of Radiology (R.V.C.), Monash Health, and Department of Surgery, Monash University, Melbourne, Australia.
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A.J. Yoo
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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T.M. Leslie-Mazwi
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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D.L. Bell
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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B.P. Mehta
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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T.L. Vanderboom
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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J.D. Rabinov
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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M. Larvie
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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J.A. Hirsch
aFrom the Department of Radiology (A.C.G., A.J.Y., T.M.L.-M., D.L.B., B.P.M., T.L.V., J.D.R., M.L., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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Abstract

BACKGROUND AND PURPOSE: Sacral insufficiency fractures are a common cause of severe low back pain and immobilization in patients with osteoporosis or cancer. Current practice guideline recommendations range from analgesia and physical therapy to resection with surgical fixation. We sought to assess the safety and effectiveness of sacroplasty, an emerging minimally invasive treatment.

MATERIALS AND METHODS: We performed a retrospective review of institutional databases for percutaneous sacroplasty performed between January 2004 and September 2013. Demographic and procedural data and pre- and posttreatment Visual Analog Scale, Functional Mobility Scale, and Analgesic Scale scores were reviewed. Overall response was rated by using a 4-point scale (1, complete resolution of pain; 2, improvement of pain; 3, no change; 4, worsened pain) assessed at short-term follow-up.

RESULTS: Fifty-three patients were included; most (83%) were female. Fracture etiology was cancer-related (55%), osteoporotic insufficiency (30%), and minor trauma (15%). No major complication or procedure-related morbidity occurred. There were statistically significant decreases in the Visual Analog Scale (P < .001), Functional Mobility Scale (P < .001), and Analgesic Scale scores (P < .01) in 27 patients with recorded data: pretreatment Visual Analog Scale (median [interquartile range], 9.0 [8.0–10.0]); Functional Mobility Scale, 3.0 (2.0–3.0); and Analgesic Scale scores, 3.0 (3.0–4.0) were reduced to 3.0 (0.0–5.8), 1.0 (0.25–2.8), and 3.0 (2.0–3.8) posttreatment. When we used the overall 4-point score at a mean of 27 days, 93% (n = 45) reported complete resolution or improvement in overall pain.

CONCLUSIONS: In this single-center cohort, sacroplasty was a safe and effective procedure. There were significant short-term gains in pain relief, increased mobility, and decreased dependence on pain medication.

ABBREVIATIONS:

AS
Analgesic Scale
FMS
Functional Mobility Scale
PMMA
polymethylmethacrylate
VAS
Visual Analog Scale
  • © 2014 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 35 (11)
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A.C. Gupta, R.V. Chandra, A.J. Yoo, T.M. Leslie-Mazwi, D.L. Bell, B.P. Mehta, T.L. Vanderboom, J.D. Rabinov, M. Larvie, J.A. Hirsch
Safety and Effectiveness of Sacroplasty: A Large Single-Center Experience
American Journal of Neuroradiology Nov 2014, 35 (11) 2202-2206; DOI: 10.3174/ajnr.A4027

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Safety and Effectiveness of Sacroplasty: A Large Single-Center Experience
A.C. Gupta, R.V. Chandra, A.J. Yoo, T.M. Leslie-Mazwi, D.L. Bell, B.P. Mehta, T.L. Vanderboom, J.D. Rabinov, M. Larvie, J.A. Hirsch
American Journal of Neuroradiology Nov 2014, 35 (11) 2202-2206; DOI: 10.3174/ajnr.A4027
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