Article Figures & Data
Figures
- Fig 1.
Aortogram of a Yucatan miniature pig (anteroposterior view). Bilateral superficial cervical arteries (arrows) and the main branches of the thyrocervical trunk are seen projecting superolaterally, branching into smaller vessels. Arrowheads indicate bilateral common carotid arteries.
- Fig 2.
A, Photograph of a surgically exposed left superficial cervical artery (left) and its selective angiogram (right). Note that multiple branches of the superficial cervical artery are seen in both the surgical view and the angiogram. B, Intraprocedural photograph (left) and an angiogram (right) of the left superficial cervical artery (postocclusion). The left superficial cervical artery shown in A was occluded with an injected experimental thrombus (left). Pulsation of the artery diminishes significantly after the occlusion, and the artery becomes pale. An angiogram was performed. C, Intraprocedural photograph (left) and an angiogram (right) of the left superficial cervical artery (Merci device deployment). A Merci clot retriever, deployed at the postbifurcation segment of the left superficial cervical artery (open arrow) and a microcatheter (arrow) are seen through the wall of the vessel (left). A fluoroscopic view of the same artery shows the device being deployed and reformed into its original coil shape (right). Behavior of the deployed device can be monitored during the procedure under direct vision.
- Fig 3.
A, Microscopic view of the arterial sample (control group) (hematoxylin-eosin [H&E] staining). A low-magnification view of the harvested arterial sample (left, original magnification ×40) demonstrates well-maintained tissue integrity throughout all layers of the vessel. A magnified view of the same sample (right, original magnification ×100) shows the general histologic characteristics of a small artery. The tunica media, which constitutes most of the arterial wall, has up to 10–12 layers of smooth muscle cells. There is a very thin layer of tunica intima lined by a layer of endothelial cells (arrows). The external elastic lamina is not distinct. The structure is quite similar to that seen in the human intracranial arteries except that the layer of the tunica media is slightly thicker in this model. B, Microscopic view of an artery treated with mechanical thrombectomy (H&E staining). A low-magnification view (left, original magnification ×40) shows the separation of the smooth muscle layers in the tunica media and migration of acute inflammatory cells between the layers (arrowheads). A magnified view of the same arterial sample (right, original magnification ×200) demonstrates aggregated platelets on the surface of the arterial wall (arrows) and acute inflammatory cells migrating into the innermost layers of the tunica media (open arrows). The findings indicate an acute inflammatory reaction induced by the mechanical thrombectomy.
In this issue
Jump to section
Related Articles
Cited By...
- Impact of Target Artery Size on the Performance of Aspiration Thrombectomy: Insights from a Swine Model with Real-Time Visualization
- Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy
- A comparison of acute vascular damage caused by ADAPT versus a stent retriever device after thrombectomy in acute ischemic stroke: a histological and ultrastructural study in an animal model
- Evaluation of the JRecan device for thrombus retrieval: efficacy and safety in a swine model of acute arterial occlusion
- Histopathologic Evaluation of Arterial Wall Response to 5 Neurovascular Mechanical Thrombectomy Devices in a Swine Model