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High Angular Resolution Diffusion Imaging Probabilistic Tractography of the Auditory Radiation

J.I. Berman, M.R. Lanza, L. Blaskey, J.C. Edgar and T.P.L. Roberts
American Journal of Neuroradiology August 2013, 34 (8) 1573-1578; DOI: https://doi.org/10.3174/ajnr.A3471
J.I. Berman
aFrom the Department of Radiology (J.I.B., M.R.L., L.B., J.C.E., T.P.L.R.), Children's Hospital of Philadelphia
bDepartment of Radiology (J.I.B., J.C.E., T.P.L.R.), University of Pennsylvania, Philadelphia, Pennsylvania.
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M.R. Lanza
aFrom the Department of Radiology (J.I.B., M.R.L., L.B., J.C.E., T.P.L.R.), Children's Hospital of Philadelphia
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L. Blaskey
aFrom the Department of Radiology (J.I.B., M.R.L., L.B., J.C.E., T.P.L.R.), Children's Hospital of Philadelphia
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J.C. Edgar
aFrom the Department of Radiology (J.I.B., M.R.L., L.B., J.C.E., T.P.L.R.), Children's Hospital of Philadelphia
bDepartment of Radiology (J.I.B., J.C.E., T.P.L.R.), University of Pennsylvania, Philadelphia, Pennsylvania.
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T.P.L. Roberts
aFrom the Department of Radiology (J.I.B., M.R.L., L.B., J.C.E., T.P.L.R.), Children's Hospital of Philadelphia
bDepartment of Radiology (J.I.B., J.C.E., T.P.L.R.), University of Pennsylvania, Philadelphia, Pennsylvania.
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  • Fig 1.
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    Fig 1.

    The starting region of interest for fiber tracking within the Heschl gyrus is shown on the left. The target region of interest on the inferior surface of the thalamus is shown on the right. The regions are shown overlaid on axial sections through the b=0 s/mm2 echo-planar volume from the 64-direction HARDI acquisition.

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    Fig 2.

    Q-ball reconstructions of the HARDI data are shown for each voxel on an axial section. HARDI fiber tracks (red streamlines) course from the AC to the thalamus. The ILF (green fiber peaks and orientation indicated with arrow) intersects the auditory radiation.

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    Fig 3.

    HARDI fiber tracks (red) and DTI fiber tracks (blue) are visualized in the left and right hemispheres. DTI fiber tracks are from the 64-direction dataset. The left hemisphere is on the left side of the figure. Both HARDI and DTI fiber tracks were launched from the same starting regions in the Heschl gyrus. The HARDI fiber tracks reaching the thalamic target regions are retained. For this figure, all DTI fiber tracks are retained regardless of destination. The DTI fiber tracks emerge from the Heschl gyrus and follow the ILF in either the anterior or posterior direction. No DTI fiber tracks cross the ILF to reach the thalamus in the right hemisphere.

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    Fig 4.

    HARDI and DTI fiber tracks connecting the AC to the thalamic target region are shown in a case where both methods were successful in each hemisphere. The number of fiber trajectories passing through each voxel is encoded with the overlay color. The yellow voxels have the highest probability of being within the auditory radiation.

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    Fig 5.

    The threshold for successful fiber-tracking is varied between 1 and 200 trajectories connecting the AC to the thalamus. The percentage of successful HARDI and DTI fiber-tracking trials is shown at each threshold. An asterisk indicates that the HARDI rate of success is significantly higher than the respective DTI fiber-tracking rate of success (P < .01).

Tables

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  • Comparison of DTI and HARDI auditory fiber-tracking results. Successful connections contained 1 or more fiber trajectories

    SuccessfulUnsuccessful
    LeftRightTotalLeftRightTotal
    DTI - 30 Directions1652192029
    DTI - 64 Directions1872571825
    HARDI - 64 Directions242549101
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American Journal of Neuroradiology: 34 (8)
American Journal of Neuroradiology
Vol. 34, Issue 8
1 Aug 2013
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Cite this article
J.I. Berman, M.R. Lanza, L. Blaskey, J.C. Edgar, T.P.L. Roberts
High Angular Resolution Diffusion Imaging Probabilistic Tractography of the Auditory Radiation
American Journal of Neuroradiology Aug 2013, 34 (8) 1573-1578; DOI: 10.3174/ajnr.A3471

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High Angular Resolution Diffusion Imaging Probabilistic Tractography of the Auditory Radiation
J.I. Berman, M.R. Lanza, L. Blaskey, J.C. Edgar, T.P.L. Roberts
American Journal of Neuroradiology Aug 2013, 34 (8) 1573-1578; DOI: 10.3174/ajnr.A3471
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