Evaluating CT Perfusion Using Outcome Measures of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage

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Fig 1.
ROC curves for each CTP parameter for the outcomes of permanent neurologic deficits (A), cerebral infarction (B), and DCI (C). Gray curves indicate the upper and lower 95% confidence intervals.
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Fig 2.
An 88-year-old woman status post surgical clipping of a left posterior communicating artery aneurysm. On day 7, she developed left upper and lower extremity motor deficits. Initial noncontrast CT (not shown) revealed no evidence of acute infarction, new hemorrhage, or hydrocephalus to explain the new onset of symptoms. CTP demonstrates a large right-sided perfusion deficit with elevated MTT (A) and reduced CBF (B) in the right MCA territory (arrows). Noncontrast CT (C) performed on day 21 shows an infarction involving the right insular region (arrows) corresponding to the CTP deficit.

Table 1:

Clinical and demographic characteristics of the study population

Table 2:

Mean quantitative CTP parameters and SD for the primary outcome measures of permanent neurologic deficits and infarction

	Neurologic Deficits (n = 32)		No Deficit (n = 64)		P Value	Infarction (n = 17)		No Infarction (n = 79)		P Value
	Mean	SD	Mean	SD	P Value	Mean	SD	Mean	SD	P Value
CBF	28.68	14	35.5	13.45	.0231	26.83	13.34	34.61	13.76	.0362
CBV	1.98	0.72	1.88	0.53	.4429	1.93	0.82	1.91	0.54	.9006
MTT	7.19	3.92	5.33	2.06	.0029	7.8	4.2	5.55	2.45	.0037