Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleHead and Neck Imaging
Open Access

Differences in Imaging Characteristics of HPV-Positive and HPV-Negative Oropharyngeal Cancers: A Blinded Matched-Pair Analysis

S.C. Cantrell, B.W. Peck, G. Li, Q. Wei, E.M. Sturgis and L.E. Ginsberg
American Journal of Neuroradiology October 2013, 34 (10) 2005-2009; DOI: https://doi.org/10.3174/ajnr.A3524
S.C. Cantrell
aFrom the Departments of Diagnostic Imaging (S.C.C., L.E.G.)
dDepartment of Radiology (S.C.C.), University of Texas Health Science Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
B.W. Peck
eDepartment of Otorhinolaryngology (B.W.P.), Mayo Clinic, Rochester, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G. Li
bEpidemiology (G.L., Q.W., E.M.S.)
cHead and Neck Surgery (G.L., E.M.S.), University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Q. Wei
bEpidemiology (G.L., Q.W., E.M.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E.M. Sturgis
bEpidemiology (G.L., Q.W., E.M.S.)
cHead and Neck Surgery (G.L., E.M.S.), University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L.E. Ginsberg
aFrom the Departments of Diagnostic Imaging (S.C.C., L.E.G.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

REFERENCES

  1. 1.↵
    1. Chaturvedi AK,
    2. Engels EA,
    3. Anderson WF,
    4. et al
    . Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol 2008;26:612–19
    Abstract/FREE Full Text
  2. 2.
    1. Carvalho AL,
    2. Nishimoto IN,
    3. Califano JA,
    4. et al
    . Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer 2005;114:806–16
    CrossRefPubMedWeb of Science
  3. 3.
    1. Shiboski CH,
    2. Schmidt BL,
    3. Jordan RC
    . Tongue and tonsil carcinoma: increasing trends in the US population ages 20–44 years. Cancer 2005;103:1843–49
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Sturgis EM,
    2. Ang KK
    . The epidemic of HPV-associated oropharyngeal cancer is here: is it time to change our treatment paradigms? J Natl Compr Canc Netw 2011;9:665–73
    Abstract/FREE Full Text
  5. 5.↵
    1. Sturgis EM,
    2. Cinciripini PM
    . Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers? Cancer 2007;110:1429–35
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Ang KK,
    2. Harris J,
    3. Wheeler R,
    4. et al
    . Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010;363:24–35
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Dahlstrom KR,
    2. Li G,
    3. Tortolero-Luna G,
    4. et al
    . Differences in history of sexual behavior between patients with oropharyngeal squamous cell carcinoma and patients with squamous cell carcinoma at other head and neck sites. Head Neck 2011;33:847–55
    CrossRefPubMed
  8. 8.
    1. D'Souza G,
    2. Kreimer AR,
    3. Viscidi R,
    4. et al
    . Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 2007;356:1944–56
    CrossRefPubMedWeb of Science
  9. 9.
    1. Gillison ML,
    2. D'Souza G,
    3. Westra W,
    4. et al
    . Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 2008;100:407–20
    Abstract/FREE Full Text
  10. 10.↵
    1. Ji X,
    2. Neumann AS,
    3. Sturgis EM,
    4. et al
    . p53 codon 72 polymorphism associated with risk of human papillomavirus-associated squamous cell carcinoma of the oropharynx in never-smokers. Carcinogenesis 2008;29:875–79
    Abstract/FREE Full Text
  11. 11.↵
    1. Klussmann JP,
    2. Mooren JJ,
    3. Lehnen M,
    4. et al
    . Genetic signatures of HPV-related and unrelated oropharyngeal carcinoma and their prognostic implications. Clin Cancer Res 2009;15:1779–86
    Abstract/FREE Full Text
  12. 12.↵
    1. Marur S,
    2. D'Souza G,
    3. Westra WH,
    4. et al
    . HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol 2010;11:781–89
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Goldenberg D,
    2. Begum S,
    3. Westra WH,
    4. et al
    . Cystic lymph node metastasis in patients with head and neck cancer: an HPV-associated phenomenon. Head Neck 2008;30:898–903
    CrossRefPubMed
  14. 14.↵
    1. Flanagan PM,
    2. Roland NJ,
    3. Jones AS
    . Cervical node metastases presenting with features of branchial cysts. J Laryngol Otol 1994;108:1068–71
    PubMed
  15. 15.
    1. Gourin CG,
    2. Johnson JT
    . Incidence of unsuspected metastases in lateral cervical cysts. Laryngoscope 2000;110:1637–41
    CrossRefPubMed
  16. 16.
    1. Regauer S,
    2. Mannweiler S,
    3. Anderhuber W,
    4. et al
    . Cystic lymph node metastases of squamous cell carinoma of Waldeyer's ring origin. Br J Cancer 1999;79:1437–42
    CrossRefPubMed
  17. 17.↵
    1. Thompson LD,
    2. Heffner DK
    . The clinical importance of cystic squamous cell carcinomas in the neck: a study of 136 cases. Cancer 1998;82:944–56
    CrossRefPubMed
  18. 18.↵
    1. Myers JN,
    2. Greenberg JS,
    3. Mo V,
    4. et al
    . Extracapsular spread: a significant predictor of treatment failure in patients with squamous cell carcinoma of the tongue. Cancer 2001;92:3030–36
    CrossRefPubMedWeb of Science
  19. 19.
    1. Wenzel S,
    2. Sagowski C,
    3. Kehrl W,
    4. et al
    . The prognostic impact of metastatic pattern of lymph nodes in patients with oral and oropharyngeal squamous cell carcinomas. Eur Arch Otorhinolaryngol 2004;261:270–75
    CrossRefPubMed
  20. 20.
    1. Iyer NG,
    2. Kim L,
    3. Nixon IJ,
    4. et al
    . Outcome of patients with early T1 and T2 squamous cell carcinoma of the base of tongue managed by conventional surgery with adjuvant postoperative radiation. Head Neck 2012 doi: 10.1002/hed.23071
  21. 21.↵
    1. Olsen KD,
    2. Caruso M,
    3. Foote RL,
    4. et al
    . Primary head and neck cancer: histopathologic predictors of recurrence after neck dissection in patients with lymph node involvement. Arch Otolaryngol Head Neck Surg 1994;120:1370–74
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Martinez I,
    2. Wang J,
    3. Hobson KF,
    4. et al
    . Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas. Eur J Cancer 2007;43:415–32
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. Weinberger PM,
    2. Yu Z,
    3. Haffty BG,
    4. et al
    . Molecular classification identifies a subset of human papillomavirus—associated oropharyngeal cancers with favorable prognosis. J Clin Oncol 2006;24:736–47
    Abstract/FREE Full Text
  24. 24.↵
    1. Kumar B,
    2. Cordell KG,
    3. Lee JS,
    4. et al
    . EGFR, p16, HPV titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer. J Clin Oncol 2008;26:3128–37
    Abstract/FREE Full Text
  25. 25.↵
    1. Hudgins PA,
    2. Gillison M
    . Second branchial cleft cyst: not!! AJNR Am J Neuroradiol 2009;9:1628–29
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 34 (10)
American Journal of Neuroradiology
Vol. 34, Issue 10
1 Oct 2013
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Differences in Imaging Characteristics of HPV-Positive and HPV-Negative Oropharyngeal Cancers: A Blinded Matched-Pair Analysis
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
S.C. Cantrell, B.W. Peck, G. Li, Q. Wei, E.M. Sturgis, L.E. Ginsberg
Differences in Imaging Characteristics of HPV-Positive and HPV-Negative Oropharyngeal Cancers: A Blinded Matched-Pair Analysis
American Journal of Neuroradiology Oct 2013, 34 (10) 2005-2009; DOI: 10.3174/ajnr.A3524

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Differences in Imaging Characteristics of HPV-Positive and HPV-Negative Oropharyngeal Cancers: A Blinded Matched-Pair Analysis
S.C. Cantrell, B.W. Peck, G. Li, Q. Wei, E.M. Sturgis, L.E. Ginsberg
American Journal of Neuroradiology Oct 2013, 34 (10) 2005-2009; DOI: 10.3174/ajnr.A3524
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Radiomics with super-voxel segmentation improves HPV prediction accuracy significantly in oropharyngeal cancer
  • Auto-Detection and Segmentation of Involved Lymph Nodes in HPV-Associated Oropharyngeal Cancer Using a Convolutional Deep Learning Neural Network
  • Correlation between Human Papillomavirus Status and Quantitative MR Imaging Parameters including Diffusion-Weighted Imaging and Texture Features in Oropharyngeal Carcinoma
  • Using Texture Analysis to Determine Human Papillomavirus Status of Oropharyngeal Squamous Cell Carcinomas on CT
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • MRI of the Parasellar Ligaments
  • ASL Sensitivity for Head and Neck Paraganglioma
  • Post SRS Peritumoral Hyperintense Signal of VSs
Show more Head and Neck Imaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire