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Research ArticleNeurointervention
Open Access

Patient-Specific Computational Hemodynamics of Intracranial Aneurysms from 3D Rotational Angiography and CT Angiography: An In Vivo Reproducibility Study

A.J. Geers, I. Larrabide, A.G. Radaelli, H. Bogunovic, M. Kim, H.A.F. Gratama van Andel, C.B. Majoie, E. VanBavel and A.F. Frangi
American Journal of Neuroradiology March 2011, 32 (3) 581-586; DOI: https://doi.org/10.3174/ajnr.A2306
A.J. Geers
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I. Larrabide
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A.G. Radaelli
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H. Bogunovic
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M. Kim
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H.A.F. Gratama van Andel
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C.B. Majoie
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E. VanBavel
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A.F. Frangi
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    Fig 1.

    Boxplot showing the distribution of differences for each geometric and hemodynamic variable among the 10 aneurysms. Outliers, marked with an asterisk, are defined as data points that are >1.5 times the interquartile range above the upper or below the lower quartile.

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    Fig 2.

    Visualizations of hemodynamic results for aneurysms 1 (A), 6 (B), 9 (C), and 10 (D). The view was chosen to most clearly present the main hemodynamic features. Displayed are streamlines color-coded with the velocity magnitude representing the flow fields at end diastole (row 1) and peak systole (row 2), the time-averaged WSS magnitude (row 3), and the OSI (row 4). Black arrows indicate the direction of flow.

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    Table 1:

    Clinical information of patient population

    PatientAneurysm
    No.SexAge (yr)No.SideLocationRupture
    1F451RightMCA M1-M2    Yes
    2LeftMCA M1-M2    No
    2F743LeftICA    Yes
    3F374RightMCA M1    No
    5RightMCA M1    No
    6RightMCA M1-M2    No
    4F437LeftMCA M1    No
    8RightMCA M1    No
    9RightMCA M1-M2    Yes
    10MidlineBA tip    No
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    Table 2:

    Intermodality and interobserver agreement for qualitative hemodynamic variables

    VariableNo. of Categoriesκmodalityκobserver
    κAgreementκAgreement
    Impingement location30.95Excellent0.76    Good
    Impingement region size21Excellent1    Excellent
    Jet size21Excellent1    Excellent
    Flow complexity20.9Excellent1    Excellent
    Flow stability20.9Excellent0.81    Excellent
    Flow pattern type30.95Excellent0.76    Good
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American Journal of Neuroradiology: 32 (3)
American Journal of Neuroradiology
Vol. 32, Issue 3
1 Mar 2011
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Cite this article
A.J. Geers, I. Larrabide, A.G. Radaelli, H. Bogunovic, M. Kim, H.A.F. Gratama van Andel, C.B. Majoie, E. VanBavel, A.F. Frangi
Patient-Specific Computational Hemodynamics of Intracranial Aneurysms from 3D Rotational Angiography and CT Angiography: An In Vivo Reproducibility Study
American Journal of Neuroradiology Mar 2011, 32 (3) 581-586; DOI: 10.3174/ajnr.A2306

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Patient-Specific Computational Hemodynamics of Intracranial Aneurysms from 3D Rotational Angiography and CT Angiography: An In Vivo Reproducibility Study
A.J. Geers, I. Larrabide, A.G. Radaelli, H. Bogunovic, M. Kim, H.A.F. Gratama van Andel, C.B. Majoie, E. VanBavel, A.F. Frangi
American Journal of Neuroradiology Mar 2011, 32 (3) 581-586; DOI: 10.3174/ajnr.A2306
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Cited By...

  • A Review of Intracranial Aneurysm Imaging Modalities, from CT to State-of-the-Art MR
  • Non-contrast enhanced silent MR angiography to evaluate hemodynamics and morphology of unruptured intracranial aneurysms: a comparative computational fluid dynamics study
  • 4D-CT angiography versus 3D-rotational angiography as the imaging modality for computational fluid dynamics of cerebral aneurysms
  • Quantitative and Qualitative Comparison of 4D-DSA with 3D-DSA Using Computational Fluid Dynamics Simulations in Cerebral Aneurysms
  • Critical role of angiographic acquisition modality and reconstruction on morphometric and haemodynamic analysis of intracranial aneurysms
  • CFD: Computational Fluid Dynamics or Confounding Factor Dissemination? The Role of Hemodynamics in Intracranial Aneurysm Rupture Risk Assessment
  • Mind the Gap: Impact of Computational Fluid Dynamics Solution Strategy on Prediction of Intracranial Aneurysm Hemodynamics and Rupture Status Indicators
  • 3D Cine Phase-Contrast MRI at 3T in Intracranial Aneurysms Compared with Patient-Specific Computational Fluid Dynamics
  • Intracranial Aneurysm Neck Size Overestimation with 3D Rotational Angiography: The Impact on Intra-Aneurysmal Hemodynamics Simulated with Computational Fluid Dynamics
  • Point: CFD--Computational Fluid Dynamics or Confounding Factor Dissemination
  • Reply:
  • Identifying "Truth" in Computational Fluid Dynamics Research
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