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Research ArticleBrainF
Open Access

MR Imaging of Partially Thrombosed Cerebral Aneurysms: Characteristics and Evolution

A.J. Martin, S.W. Hetts, W.P. Dillon, R.T. Higashida, V. Halbach, C.F. Dowd, M.T. Lawton and D. Saloner
American Journal of Neuroradiology February 2011, 32 (2) 346-351; DOI: https://doi.org/10.3174/ajnr.A2298
A.J. Martin
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S.W. Hetts
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W.P. Dillon
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R.T. Higashida
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V. Halbach
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C.F. Dowd
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M.T. Lawton
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D. Saloner
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    Fig 1.

    A, MIP of a contrast-enhanced angiogram of a right vertebral artery aneurysm. B and C, Matched sections from the SSFP image (B) and the angiogram (C) reveal a thrombosed component to the aneurysm (arrow in B), which indicates a substantially larger aneurysm than can be appreciated on the angiogram alone.

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    Fig 2.

    The relative image contrast achieved with T1-weighted (A), T2-weighted (B), and SSFP (C) images are shown for this partially thrombosed basilar aneurysm. A matched section from the CE-MRA (D) reveals the free lumen (asterisks in A–C) and the thrombosed region (arrows in A–C).

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    Fig 3.

    This summary array shows examples of the matched regions of interest that were used to establish relative signal intensities of thrombus core and rim, blood, CSF, and brain on T2-weighted (A), T1-weighted (B), and SSFP (C) images. Signal intensities were normalized to those of brain in a region devoid of CSF based on the SSFP and T2-weighted images. The evolution of thrombus during a 1-year interval is also demonstrated in SSFP images (C and D). Both images are at the same level of the aneurysm, though there is a slight difference in the obliquity of the axial plane. The hyperintense outer rim of the thrombosed region of the aneurysm (arrows) is evident in both studies, and the general contrast properties of the thrombus remain remarkably consistent during this interval.

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    Fig 4.

    This partially thrombosed (arrows) basilar aneurysm is demonstrated on postcontrast T1-weighted (A), SSFP (B), CE-MRA (C), and T2-weighted (D) images. These matched oblique coronal scanning planes reveal the extent of thrombosis and further indicate delayed enhancement of the arterial wall underlying the thrombosis (A).

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    Table 1:

    Signal-intensity analysis of aneurysm thrombus: signal intensities normalized to braina

    TissueT1-WeightedT2-WeightedSteady-State
    Thrombus core1.1 ± 0.30.6 ± 0.31.1 ± 0.3
    Thrombus rim1.5 ± 0.20.6 ± 0.22.3 ± 0.3
    Blood1.0 ± 0.31.4 ± 0.84.3 ± 1.7
    CSF0.5 ± 0.13.6 ± 0.27.2 ± 0.9
    • a Thrombus heterogeneity with a rim evident occurred in 4/9 subjects.

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    Table 2:

    Evolution of thrombus SSFP signal intensities with timea

    StudyThrombus CoreThrombus RimBloodCSF
    Baseline1.1 ± 0.32.3 ± 0.34.3 ± 1.77.2 ± 0.9
    Follow-up1.0 ± 0.12.2 ± 0.74.3 ± 2.67.2 ± 1.4
    • a Thrombus heterogeneity with a rim evident occurred in 4/9 subjects.

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American Journal of Neuroradiology: 32 (2)
American Journal of Neuroradiology
Vol. 32, Issue 2
1 Feb 2011
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Cite this article
A.J. Martin, S.W. Hetts, W.P. Dillon, R.T. Higashida, V. Halbach, C.F. Dowd, M.T. Lawton, D. Saloner
MR Imaging of Partially Thrombosed Cerebral Aneurysms: Characteristics and Evolution
American Journal of Neuroradiology Feb 2011, 32 (2) 346-351; DOI: 10.3174/ajnr.A2298

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MR Imaging of Partially Thrombosed Cerebral Aneurysms: Characteristics and Evolution
A.J. Martin, S.W. Hetts, W.P. Dillon, R.T. Higashida, V. Halbach, C.F. Dowd, M.T. Lawton, D. Saloner
American Journal of Neuroradiology Feb 2011, 32 (2) 346-351; DOI: 10.3174/ajnr.A2298
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