Article Figures & Data
Figures
- Fig 1.
Procedural duration and number of passes stratified by the final TIMI score. A, Mean procedural duration (hours) stratified by final TIMI score. B, Percentage of cases in which ≥4 passes with the Merci retriever were made, stratified by final TIMI score.
- Fig 2.
Distribution of functional outcome stratified by TIMI score.
- Fig 3.
Unadjusted absolute likelihood of a favorable functional outcome and mortality as a function of TIMI score.
- Fig 4.
The effect of each increase of TIMI score on the odds of favorable functional outcome and survival. A, Unadjusted ORs for favorable functional outcome (mRS score of 0–2) as the TIMI grade increases from 0 to 3. B, Unadjusted ORs for survival to 90 days as TIMI grade increases from 0 to 3.
Tables
TIMI 0 TIMI 1 TIMI 2 TIMI 3 Total P No. of patients 110 20 61 114 305 Age (yr) Mean 68.1 ± 15 64.5 ± 16 70.5 ± 14.9 66.1 ± 16.7 67.6 ± 15.8 NS Median (IQR) 73 (59.0–80.0) 66 (54.0–77.5) 75 (63.0–81.0) 70 (55.0–79.0) 72 (58.0–80.0) Female 55.5% 55.0% 52.5% 48.2% 52.1% NS Vessel involved Vertebrobasilar 6.4% 15.0% 6.6% 12.3% 9.2% NS Carotid 32.7% 30.0% 27.9% 35.1% 32.5% MCA (M1/M2) 60.9% 55.0% 65.6% 52.6% 58.4% NIHSS score (median) (IQR) 20 (16.0–24.0) 19 (14.0–22.5) 17 (14.0–23.0) 18 (15.0–23.0) 19 (15.0–23.0) NS Baseline mRS (0 or 1) 89.1% 75.0% 83.6% 92.9% 88.5% NS Note:—IQR indicates interquartile range; NS, not significant.
TIMI 0 TIMI 1 TIMI 2 TIMI 3 Total P Value No. of patients 110 20 61 114 305 Ictus to arterial puncture (hr) (mean) Median (IQR) 4.5 ± 2.1 4.5 ± 1.6 4.3 ± 1.6 4.2 ± 1.5 4.4 ± 1.8 NS 4.3 (3.0–5.6) 4.1 (3.3–5.4) 4.4 (3.2–5.7) 4.2 (3.1–5.2) 4.3 (3.1–5.5) Ictus to procedure end (hr) (mean) Median (IQR) 6.6 ± 2.1 6.93 ± 2.0 6.3 ± 1.9 5.8 ± 1.6 6.3 ± 1.9 .004 6.5 (5.5–7.8) 7.1 (5.7–8.2) 6.0 (5.0–7.7) 5.8 (4.7–6.9) 6.1 (5.0–7.5) No. of passes 1 9.1% 25.0% 31.1% 34.2% 23.9% <.001 2 18.2% 15.0% 16.4% 23.7% 19.7% 3 30.0% 15.0% 21.3% 22.8% 24.6% 4 13.6% 5.0% 19.7% 11.4% 13.4% >4 29.1% 40% 11.5% 7.9% 18.4% Use of adjuvant 40.9% 45.0% 32.8% 36.0% 37.7% NS Procedure-related clinically significant AE 10.0% 0.0% 6.6% 3.5% 6.2% .09 Symptomatic bleeding events 12.7% 10.0% 8.2% 5.3% 8.9% NS PH-2 events 9.1% 0.0% 3.2% 3.7% 4.9% NS Note:—IQR indicates interquartile range; NS, not significant; AE, adverse events.
OR (95% CI) P Value Final TIMI flow (0, 1, 2, 3) 2.6 (1.9–3.4) <.0001 NIHSS score 0.89 (0.84–0.94) <.0001 Age (yr) 0.97 (0.95–0.98) .0003
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