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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

High-Resolution In Utero 3D MR Imaging of Inner Ear Microstructures in Fetal Sheep

J.-H. Buhk, M. Frisch, J. Yamamura, J. Graessner, G. Adam and U. Wedegärtner
American Journal of Neuroradiology December 2011, 32 (11) 2043-2046; DOI: https://doi.org/10.3174/ajnr.A2736
J.-H. Buhk
aFrom the Department of Diagnostic and Interventional Radiology (J.-H.B., M.F., J.Y., G.A., U.W.), University Medical Center Hamburg Eppendorf, Hamburg, Germany
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M. Frisch
aFrom the Department of Diagnostic and Interventional Radiology (J.-H.B., M.F., J.Y., G.A., U.W.), University Medical Center Hamburg Eppendorf, Hamburg, Germany
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J. Yamamura
aFrom the Department of Diagnostic and Interventional Radiology (J.-H.B., M.F., J.Y., G.A., U.W.), University Medical Center Hamburg Eppendorf, Hamburg, Germany
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J. Graessner
bSiemens Healthcare (J.G.), Hamburg, Germany.
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G. Adam
aFrom the Department of Diagnostic and Interventional Radiology (J.-H.B., M.F., J.Y., G.A., U.W.), University Medical Center Hamburg Eppendorf, Hamburg, Germany
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U. Wedegärtner
aFrom the Department of Diagnostic and Interventional Radiology (J.-H.B., M.F., J.Y., G.A., U.W.), University Medical Center Hamburg Eppendorf, Hamburg, Germany
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    Fig 1.

    Coronal view (thin-section MIP; section thickness, 0.5 mm) shows the normally developed cochlea (open arrows) and the tympanic cavity (closed arrows), which are both (normal findings in utero) fluid-filled in the reference examination (A, 3D CISS, stillborn lamb) as well as in vivo (B, 3D True FISP).

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    Fig 2.

    This set of axial views of the reference examination (A, 3D CISS, stillborn lamb) and in vivo (B, 3D True FISP; both thin-section MIPs; section thickness, 0.7 mm) displays the IAM with the seventh and eighth cranial nerve (arrows) and a cross-section through the normally developed cochlear modiolus, which is also well-depicted.

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    Fig 3.

    The axial views of the reference examination (A, 3D CISS, stillborn lamb) and in vivo (B, 3D True FISP; both thin-section MIPs; section thickness, 2.0 mm) display the utriculus (open arrows) and the medial section of the posterior semicircular canal (closed arrows). The utricular ostium of the lateral semicircular canal can be seen as well in both images.

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  • Scores regarding the identification of the anatomic structures and of the assessment of the artifacts loada

    AnimalCochleaUtriculusLateral CanalAnterior CanalPosterior CanalIAMbArtifacts
    A441243Moderate
    B441144Unremarkable
    C552145Unremarkable
    D331113Severe
    E441133Moderate
    F551144Moderate
    Ref.553353Unremarkable
    • Note:—Ref. indicates reference; 1, not visible; 2, visible, not diagnostic; 3, moderate but sufficient; 4, good quality; 5, excellent quality.

    • ↵a First, the depictability of the lateral and anterior semicircular canals is also moderate in the reference examination and, therefore, likely to be a normal anatomic finding at that stage of development. Second, severe artifacts only occurred in animal D due to breech presentation of the fetus.

    • b Scoring includes visibility of cranial nerves VII and VIII.

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American Journal of Neuroradiology: 32 (11)
American Journal of Neuroradiology
Vol. 32, Issue 11
1 Dec 2011
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Cite this article
J.-H. Buhk, M. Frisch, J. Yamamura, J. Graessner, G. Adam, U. Wedegärtner
High-Resolution In Utero 3D MR Imaging of Inner Ear Microstructures in Fetal Sheep
American Journal of Neuroradiology Dec 2011, 32 (11) 2043-2046; DOI: 10.3174/ajnr.A2736

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High-Resolution In Utero 3D MR Imaging of Inner Ear Microstructures in Fetal Sheep
J.-H. Buhk, M. Frisch, J. Yamamura, J. Graessner, G. Adam, U. Wedegärtner
American Journal of Neuroradiology Dec 2011, 32 (11) 2043-2046; DOI: 10.3174/ajnr.A2736
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