Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

  • Getting new auth cookie, if you see this message a lot, tell someone!
  • Getting new auth cookie, if you see this message a lot, tell someone!
Research ArticleBrain

Cognitive Functions and White Matter Tract Damage in Amyotrophic Lateral Sclerosis: A Diffusion Tensor Tractography Study

L. Sarro, F. Agosta, E. Canu, N. Riva, A. Prelle, M. Copetti, G. Riccitelli, G. Comi and M. Filippi
American Journal of Neuroradiology November 2011, 32 (10) 1866-1872; DOI: https://doi.org/10.3174/ajnr.A2658
L. Sarro
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F. Agosta
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E. Canu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N. Riva
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Prelle
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Copetti
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G. Riccitelli
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G. Comi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Filippi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Phukan J,
    2. Pender NP,
    3. Hardiman O
    . Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurol 2007;6:994–1003
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Agosta F,
    2. Chio A,
    3. Cosottini M,
    4. et al
    . The present and the future of neuroimaging in amyotrophic lateral sclerosis. AJNR Am J Neuroradiol 2010;31:1769–77
    Abstract/FREE Full Text
  3. 3.↵
    1. Chang JL,
    2. Lomen-Hoerth C,
    3. Murphy J,
    4. et al
    . A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD. Neurology 2005;65:75–80
    Abstract/FREE Full Text
  4. 4.↵
    1. Abrahams S,
    2. Goldstein LH,
    3. Suckling J,
    4. et al
    . Frontotemporal white matter changes in amyotrophic lateral sclerosis. J Neurol 2005;252:321–31
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Brooks BR
    . El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial “Clinical limits of amyotrophic lateral sclerosis” workshop contributors. J Neurol Sci 1994;124 Suppl:96–107
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Neary D,
    2. Snowden JS,
    3. Gustafson L,
    4. et al
    . Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998;51:1546–54
    Abstract/FREE Full Text
  7. 7.↵
    1. Cedarbaum JM,
    2. Stambler N,
    3. Malta E,
    4. et al
    . The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci 1999;169:13–21
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. de Carvalho M,
    2. Scotto M,
    3. Lopes A,
    4. et al
    . Clinical and neurophysiological evaluation of progression in amyotrophic lateral sclerosis. Muscle Nerve 2003;28:630–33
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Turner MR,
    2. Cagnin A,
    3. Turkheimer FE,
    4. et al
    . Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol Dis 2004;15:601–09
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Folstein MF,
    2. Folstein SE,
    3. McHugh PR
    . “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189–98
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Carlesimo GA,
    2. Caltagirone C,
    3. Gainotti G
    . The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. The Group for the Standardization of the Mental Deterioration Battery. Eur Neurol 1996;36:378–84
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Caffarra P,
    2. Vezzadini G,
    3. Dieci F,
    4. et al
    . Rey-Osterrieth complex figure: normative values in an Italian population sample. Neurol Sci 2002;22:443–47
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Giovagnoli AR,
    2. Del Pesce M,
    3. Mascheroni S,
    4. et al
    . Trail making test: normative values from 287 normal adult controls. Ital J Neurol Sci 1996;17:305–09
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Barbarotto R,
    2. Laiacona M,
    3. Frosio R,
    4. et al
    . A normative study on visual reaction times and two Stroop colour-word tests. Ital J Neurol Sci 1998;19:161–70
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Laiacona M,
    2. Inzaghi MG,
    3. De Tanti A,
    4. et al
    . Wisconsin card sorting test: a new global score, with Italian norms, and its relationship with the Weigl sorting test. Neurol Sci 2000;21:279–91
    CrossRefPubMed
  16. 16.↵
    1. Novelli G,
    2. Papagno C,
    3. Capitani E,
    4. et al
    . Tre test clinici di ricerca e produzione lessicale. Taratura su soggetti normali. Arch Psicol Neurol Psichiatr 1986;47:477–506
  17. 17.↵
    1. Cummings JL,
    2. Mega M,
    3. Gray K,
    4. et al
    . The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994;44:2308–14
    Abstract/FREE Full Text
  18. 18.↵
    1. Strong MJ,
    2. Grace GM,
    3. Freedman M,
    4. et al
    . Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2009;10:131–46
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Filippi M,
    2. Cercignani M,
    3. Inglese M,
    4. et al
    . Diffusion tensor magnetic resonance imaging in multiple sclerosis. Neurology 2001;56:304–11
    Abstract/FREE Full Text
  20. 20.↵
    1. Zakzanis KK,
    2. Mraz R,
    3. Graham SJ
    . An fMRI study of the Trail Making Test. Neuropsychologia 2005;43:1878–86
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Kew JJ,
    2. Goldstein LH,
    3. Leigh PN,
    4. et al
    . The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study. Brain 1993;116(Pt 6):1399–423
    Abstract/FREE Full Text
  22. 22.↵
    1. Abrahams S,
    2. Goldstein LH,
    3. Kew JJ,
    4. et al
    . Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study. Brain 1996;119(Pt 6):2105–20
    Abstract/FREE Full Text
  23. 23.↵
    1. Abrahams S,
    2. Leigh PN,
    3. Harvey A,
    4. et al
    . Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia 2000;38:734–47
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Abrahams S,
    2. Goldstein LH,
    3. Simmons A,
    4. et al
    . Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain 2004;127:1507–17
    Abstract/FREE Full Text
  25. 27.↵
    1. Schermuly I,
    2. Fellgiebel A,
    3. Wagner S,
    4. et al
    . Association between cingulum bundle structure and cognitive performance: an observational study in major depression. Eur Psychiatry 25:355–60
  26. 26.↵
    1. Sexton CE,
    2. Mackay CE,
    3. Lonie JA,
    4. et al
    . MRI correlates of episodic memory in Alzheimer's disease, mild cognitive impairment, and healthy aging. Psychiatry Res 184:57–62
  27. 27.↵
    1. Nestor PG,
    2. Kubicki M,
    3. Kuroki N,
    4. et al
    . Episodic memory and neuroimaging of hippocampus and fornix in chronic schizophrenia. Psychiatry Res 2007;155:21–28
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Parker GJ,
    2. Luzzi S,
    3. Alexander DC,
    4. et al
    . Lateralization of ventral and dorsal auditory-language pathways in the human brain. Neuroimage 2005;24:656–66
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 32 (10)
American Journal of Neuroradiology
Vol. 32, Issue 10
1 Nov 2011
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Cognitive Functions and White Matter Tract Damage in Amyotrophic Lateral Sclerosis: A Diffusion Tensor Tractography Study
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
L. Sarro, F. Agosta, E. Canu, N. Riva, A. Prelle, M. Copetti, G. Riccitelli, G. Comi, M. Filippi
Cognitive Functions and White Matter Tract Damage in Amyotrophic Lateral Sclerosis: A Diffusion Tensor Tractography Study
American Journal of Neuroradiology Nov 2011, 32 (10) 1866-1872; DOI: 10.3174/ajnr.A2658

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Cognitive Functions and White Matter Tract Damage in Amyotrophic Lateral Sclerosis: A Diffusion Tensor Tractography Study
L. Sarro, F. Agosta, E. Canu, N. Riva, A. Prelle, M. Copetti, G. Riccitelli, G. Comi, M. Filippi
American Journal of Neuroradiology Nov 2011, 32 (10) 1866-1872; DOI: 10.3174/ajnr.A2658
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • MegaTrack: a framework for the anatomically accurate and time-efficient virtual dissection and analysis of large-scale tractography datasets
  • Unraveling Shared Pathways: A Comprehensive Systematic Review of Common Fiber Tracts in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia using Diffusion Tensor Imaging
  • ALS-specific cognitive and behavior changes associated with advancing disease stage in ALS
  • A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis
  • Functional pattern of brain FDG-PET in amyotrophic lateral sclerosis
  • Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
  • Quiet PROPELLER MRI Techniques Match the Quality of Conventional PROPELLER Brain Imaging Techniques
  • Predictors of Reperfusion in Patients with Acute Ischemic Stroke
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire