Article Figures & Data
Figures
- Fig 1.
A subject recording of ΔICP and ICP from a constant pressure lumbar CSF infusion test. The RPPC is the slope of the linear regression line between ΔICP and ICP. P0 is calculated as the pressure at which this line intersects with ΔICP = 0.
- Fig 2.
An overview of how the infusion and MR imaging modalities are combined to estimate compliance indices.
- Fig 3.
A, Total cerebral arterial blood flow (summated flow of the internal carotid and vertebral arteries). B, Cumulative integration of the curve in A with the average flow subtracted yields the arterial volume change during a cardiac cycle. ΔVART was defined as the largest volume difference during a cardiac cycle.
- Fig 4.
An ICP recording from a lumbar CSF infusion test. A, Baseline ICP recording. B, Infusion to predetermined ICP levels. C, Relaxation phase allowing ICP to normalize. D, A bolus test (rapid infusion of a 5.6-mL artificial CSF).
- Fig 5.
The craniospinal PVI calculated from combined MR imaging and infusion (y-xis) and from the bolus test (x-axis). The difference was not statistically different from zero, P = .83 from a paired t test. There was no significant correlation after excluding 2 extreme values (dashed contours) (P = .8778).
Tables
Reports of PVICC in various states
Subjects PVICC (mL) Method Normal pressure hydrocephalus (n = 69)16 16.4 Repeated bolus injections Idiopathic normal pressure hydrocephalus (n = 47)16 16.7 Repeated bolus injections Head injury: ICP, <20 mm Hg (n = 9)18 20.8 Bolus injection/CSF withdrawal Hydrocephalus, ventriculomegaly (n = 27)19 9.6 Constant-rate infusion Hydrocephalus, ventriculomegaly (n = 27)19 16.5 Relaxation preceding infusion Mechanically ventilated, pathologic autoregulation (n = 35)34 20.0 Bolus injection Mechanically ventilated, functioning autoregulation (n = 24)34 31.6 Bolus injection Hydrocephalus, ventriculomegaly (n = 46)20 8.9 Constant-rate infusion Adult patients without intracranial masses (n = 7)1 25.9 Bolus injection/CSF withdrawal
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