Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention

Therapeutic Results of Intra-Arterial Thrombolysis after Full-Dose Intravenous Tissue Plasminogen Activator Administration

D.-S. Yoo, Y.-D. Won, P.-W. Huh, H.-E. Shin, K.-T. Kim, S.-G. Kang, S.-B. Lee and K.-S. Cho
American Journal of Neuroradiology September 2010, 31 (8) 1536-1540; DOI: https://doi.org/10.3174/ajnr.A2084
D.-S. Yoo
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Y.-D. Won
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.-W. Huh
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H.-E. Shin
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K.-T. Kim
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.-G. Kang
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.-B. Lee
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K.-S. Cho
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Abe O,
    2. Aoki S,
    3. Shirouzu I,
    4. et al
    . MR imaging of ischemic penumbra. Eur J Radiol 2003;46:67–78
    CrossRefPubMed
  2. 2.↵
    Tissue plasminogen activator for acute ischemic stroke: The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. New Engl J Med 1995;333:1581–87
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Hacke W,
    2. Kaste M,
    3. Fieschi C,
    4. et al.
    , for the ECASS Study Group. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: The European Cooperative Acute Stroke Study (ECASS). JAMA 1995;274:1017–25
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Adams HP Jr.,
    2. del Zoppo G,
    3. Alberts MJ,
    4. et al
    . Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups—the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke 2007;38:1655–711. Epub 2007 Apr 12
    Abstract/FREE Full Text
  5. 5.↵
    1. Bourekas EC,
    2. Slivka AP,
    3. Shah R,
    4. et al
    . Intraarterial thrombolytic therapy within 3 hours of the onset of stroke. Neurosurgery 2004;54:39–46
    PubMedWeb of Science
  6. 6.↵
    1. Suarez JI,
    2. Zaidat OO,
    3. Sunshine JL,
    4. et al
    . Endovascular administration after intravenous infusion of thrombolytic agents for the treatment of patients with acute ischemic strokes. Neurosurgery 2002;50:251–60
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Madden K
    . Optimal timing of thrombolytic therapy in acute ischaemic stroke. CNS Drugs 2002;16:213–18
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Kase CS,
    2. Furlan AJ,
    3. Wechsler LR,
    4. et al
    . Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial. Neurology 2001;57:1603–10
    Abstract/FREE Full Text
  9. 9.↵
    1. Macleod MR,
    2. Davis SM,
    3. Mitchell PJ,
    4. et al
    . Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke. Cerebrovasc Dis 2005;20:12–17. Epub 2005 May 30
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Mazighi M,
    2. Serfaty JM,
    3. Labreuche J,
    4. et al.
    , for the RECANALISE investigators. Comparison of intravenous alteplase with a combined intravenous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): a prospective cohort study. Lancet Neurol 2009;8:802–09. Epub 2009 Jul 31
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Lewandowski CA,
    2. Frankel M,
    3. Tomsick TA,
    4. et al
    . Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial. Stroke 1999;30:2598–605
    Abstract/FREE Full Text
  12. 12.↵
    IMS Study Investigators. Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. Stroke 2004;35:904–11. Epub 2004 Mar 11
    Abstract/FREE Full Text
  13. 13.↵
    IMS II Trial Investigators. The Interventional Management of Stroke (IMS) II Study. Stroke 2007;38:2127–35. Epub 2007 May 24
    Abstract/FREE Full Text
  14. 14.↵
    1. Grandin CB
    . Assessment of brain perfusion with MRI: methodology and application to acute stroke. Neuroradiology 2003;45:755–66
    CrossRefPubMed
  15. 15.↵
    1. Albers GW,
    2. Thijs VN,
    3. Wechsler L,
    4. et al.
    , for the DEFUSE investigators. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol 2006;60:508–17
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Singer OC,
    2. Du Mesnil De Rochemont R,
    3. Foerch C,
    4. et al
    . Early functional recovery and the fate of the diffusion/perfusion mismatch in patients with proximal middle cerebral artery occlusion. Cerebrovasc Dis 2004;17:13–20. Epub 2003 Oct 3
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Masdeu JC,
    2. Irimia P,
    3. Asenbaum S,
    4. et al
    . EFNS guideline on neuroimaging in acute stroke: report of an EFNS task force. Eur J Neurol 2006;13:1271–83
    CrossRefPubMed
  18. 18.↵
    1. Schellinger PD,
    2. Jansen O,
    3. Fiebach JB,
    4. et al
    . Monitoring intravenous recombinant tissue plasminogen activator thrombolysis for acute ischemic stroke with diffusion and perfusion MRI. Stroke 2000;31:1318–28
    Abstract/FREE Full Text
  19. 19.↵
    1. Schellinger PD,
    2. Thomalla G,
    3. Fiehler J,
    4. et al
    . MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows: an analysis of 1210 patients. Stroke 2007;38:2640–45
    Abstract/FREE Full Text
  20. 20.↵
    1. Kane I,
    2. Sandercock P,
    3. Wardlaw J
    . Magnetic resonance perfusion diffusion mismatch and thrombolysis in acute ischaemic stroke: a systematic review of the evidence to date. J Neurol Neurosurg Psychiatry 2007;78:485–90
    Abstract/FREE Full Text
  21. 21.↵
    1. Davis SM,
    2. Donnan GA,
    3. Parsons MW,
    4. et al.
    , for the EPITHET investigators. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol 2008;7:299–309. Epub 2008 Feb 28
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Grandin CB,
    2. Duprez TP,
    3. Smith AM,
    4. et al
    . Which MR-derived perfusion parameters are the best predictors of infarct growth in hyperacute stroke? Comparative study between relative and quantitative measurements. Radiology 2002;223:361–70
    CrossRefPubMed
  23. 23.↵
    1. Yoon W,
    2. Seo JJ,
    3. Kim JK,
    4. et al
    . Contrast enhancement and contrast extravasation on computed tomography after intra-arterial thrombolysis in patients with acute ischemic stroke. Stroke 2004;35:876–81
    Abstract/FREE Full Text
  24. 24.↵
    1. Kim KT,
    2. Park JK,
    3. Kang SG,
    4. et al
    . Comparison of the effect of decompressive craniectomy on different neurosurgical diseases. Acta Neurochir (Wien) 2009;151:21–30
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Astrup J,
    2. Siesjö BK,
    3. Symon L
    . Thresholds in cerebral ischemia: the ischemic penumbra. Stroke 1981;12:723–25
    FREE Full Text
  26. 26.↵
    1. Heiss WD,
    2. Grond M,
    3. Thiel A,
    4. et al
    . Tissue at risk of infarction rescued by early reperfusion: a positron emission tomography study in systemic recombinant tissue plasminogen activator thrombolysis of acute stroke. J Cereb Blood Flow Metab 1998;18:1298–307
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Furlan M,
    2. Marchal G,
    3. Viader F,
    4. et al
    . Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra. Ann Neurol 1997;41:411–14
    CrossRefPubMed
  28. 28.↵
    1. Neumann-Haefelin T,
    2. du Mesnil de Rochemont R,
    3. Fiebach JB,
    4. et al.
    , for the Kompetenznetz Schlaganfall Study Group. Effect of incomplete (spontaneous and postthrombolytic) recanalization after middle cerebral artery occlusion: a magnetic resonance imaging study. Stroke 2004;35:109–14. Epub 2003 Dec 11
    Abstract/FREE Full Text
  29. 29.↵
    1. Rha JH,
    2. Saver JL
    . The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 2007;38:967–73
    Abstract/FREE Full Text
  30. 30.↵
    1. Lee DH,
    2. Jo KD,
    3. Kim HG,
    4. et al
    . Local intraarterial urokinase thrombolysis of acute ischemic stroke with or without intravenous abciximab: a pilot study. J Vasc Interv Radiol 2002;13:769–74
    CrossRefPubMed
  31. 31.↵
    1. Furlan A,
    2. Higashida R,
    3. Wechsler L,
    4. et al
    . Intra-arterial prourokinase for acute ischemic stroke: The PROACT II study—a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 1999;282:2003–11
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Paciaroni M,
    2. Agnelli G,
    3. Corea F,
    4. et al
    . Early hemorrhagic transformation of brain infarction: rate, predictive factors, and influence on clinical outcome—results of a prospective multicenter study. Stroke 2008;39:2249–56
    Abstract/FREE Full Text
  33. 33.↵
    1. Mielke O,
    2. Wardlaw J,
    3. Liu M
    . Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke. Cochrane Database Syst Rev 2004;18:CD000514
  34. 34.↵
    1. Abou-Chebl A,
    2. Bajzer CT,
    3. Krieger DW,
    4. et al
    . Multimodal therapy for the treatment of severe ischemic stroke combining GPIIb/IIIa antagonists and angioplasty after failure of thrombolysis. Stroke 2005;36:2286–88. Epub 2005 Sep 22
    Abstract/FREE Full Text
  35. 35.↵
    1. Rashdan I,
    2. Schechter E
    . Safety and efficacy of abciximab use in conjunction with intracoronary urokinase in patients requiring angioplasty. Catheter Cardiovasc Interv 2000;49:113–16
    CrossRefPubMedWeb of Science
  36. 36.↵
    1. Qureshi AI,
    2. Suri MF,
    3. Khan J,
    4. et al
    . Abciximab as an adjunct to high-risk carotid or vertebrobasilar angioplasty: preliminary experience. Neurosurgery 2000;46:1316–24
    CrossRefPubMedWeb of Science
  37. 37.↵
    1. Ringleb PA,
    2. Schellinger PD,
    3. Schranz C,
    4. et al
    . Thrombolytic therapy within 3 to 6 hours after onset of ischemic stroke: useful or harmful? Stroke 2002;33:1437–41
    Abstract/FREE Full Text
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 31 (8)
American Journal of Neuroradiology
Vol. 31, Issue 8
1 Sep 2010
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Therapeutic Results of Intra-Arterial Thrombolysis after Full-Dose Intravenous Tissue Plasminogen Activator Administration
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
D.-S. Yoo, Y.-D. Won, P.-W. Huh, H.-E. Shin, K.-T. Kim, S.-G. Kang, S.-B. Lee, K.-S. Cho
Therapeutic Results of Intra-Arterial Thrombolysis after Full-Dose Intravenous Tissue Plasminogen Activator Administration
American Journal of Neuroradiology Sep 2010, 31 (8) 1536-1540; DOI: 10.3174/ajnr.A2084

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Therapeutic Results of Intra-Arterial Thrombolysis after Full-Dose Intravenous Tissue Plasminogen Activator Administration
D.-S. Yoo, Y.-D. Won, P.-W. Huh, H.-E. Shin, K.-T. Kim, S.-G. Kang, S.-B. Lee, K.-S. Cho
American Journal of Neuroradiology Sep 2010, 31 (8) 1536-1540; DOI: 10.3174/ajnr.A2084
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Rescue Reentry in Carotid Near-Occlusion
  • Contour Neurovascular System: Five Year Follow Up
  • Effect of SARS-CoV2 on Endovascular Thrombectomy
Show more Neurointervention

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire