Article Figures & Data
Figures
- Fig 1.
Visualization of DTI fiber tracts through the right hemispheric internal capsule with FA coloring of the fibers from a lateral viewpoint. Top row: 5 representative control subjects. Bottom row: 4 selected Krabbe subjects. Visually, all Krabbe subjects show lower FA values along most of the fiber bundle than any of the controls.
- Fig 2.
Raw FA mean values for patients with infantile Krabbe disease and controls. Each point represents a child's mean FA across the central portion of the corticospinal tract. The red triangles represent the 6 patients with Krabbe disease, whereas the blue diamonds show the typical controls. The red and blue lines represent the linear trend related to corrected age at the time of the MR imaging.
- Fig 3.
Normalized FA ratios for patients with infantile Krabbe disease and controls. The FA ratio is the observed FA divided by the expected FA. given the child's gestational age at birth, corrected age at scanning, birth weight, and sex. The red triangles represent the 6 patients with Krabbe disease, whereas the blue diamonds show the typical controls. The horizontal black lines represent the SDs based on the controls.
Tables
- Table 1:
Descriptive information for patients with infantile Krabbe disease and healthy controls
Descriptive Information Krabbe (n = 6) Controls (n = 45) Mean SD Mean SD Birth weight (g) 3.13 0.65 3.45 0.45 Gestational age birth (wk) 38.3 1.5 39.7 1.0 Gestational age at scanning (wk) 40.1 1.9 42.9 1.7 Male 50% 60% White 100% 84% Variable Krabbe Controls Mean SD Mean SD Right Mean FA 0.36 0.04 0.45 0.04 FA ratio 0.87 0.09 1.00 0.08 Left Mean FA 0.36 0.04 0.43 0.04 FA ratio 0.89 0.09 1.00 0.08 Note:—FA indicates fractional anisotropy.
