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Research ArticlePEDIATRICS

Do Apparent Diffusion Coefficient Measurements Predict Outcome in Children with Neonatal Hypoxic-Ischemic Encephalopathy?

L. Liauw, G. van Wezel-Meijler, S. Veen, M.A. van Buchem and J. van der Grond
American Journal of Neuroradiology February 2009, 30 (2) 264-270; DOI: https://doi.org/10.3174/ajnr.A1318
L. Liauw
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G. van Wezel-Meijler
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S. Veen
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M.A. van Buchem
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J. van der Grond
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References

  1. ↵
    Cowan F, Rutherford M, Groenendaal F, et al. Origin and timing of brain lesions in term infants with neonatal encephalopathy. Lancet 2003;361:736–42
    CrossRefPubMedWeb of Science
  2. ↵
    Cowan F. Outcome after intrapartum asphyxia in term infants. Semin Neonatol 2000;5:127–40
    CrossRefPubMed
  3. ↵
    Rutherford MA. The asphyxiated term infant. In: Rutherford MA, ed. MRI of the Neonatal Brain. London: WB Saunders;2002 :99–128
  4. ↵
    Rutherford MA, Pennock JM, Counsell SJ, et al. Abnormal magnetic resonance signal in the internal capsule predicts poor neurodevelopmental outcome in infants with hypoxic-ischemic encephalopathy. Pediatrics 1998;102:323–28
    Abstract/FREE Full Text
  5. ↵
    Cowan FM, de Vries LS. The internal capsule in neonatal imaging. Semin Fetal Neonatal Med 2005;10:461–74
    PubMedWeb of Science
  6. ↵
    Barkovich AJ. Brain and spine injuries in infancy and childhood. In: Barkovich AJ, ed. Pediatric Neuroimaging. Philadelphia: Lippincott Williams & Wilkins;2005 :190–290
  7. ↵
    Rutherford M, Pennock J, Schwieso J, et al. Hypoxic-ischaemic encephalopathy: early and late magnetic resonance imaging findings in relation to outcome. Arch Dis Child Fetal Neonatal Ed 1996;75:F145–51
    Abstract/FREE Full Text
  8. ↵
    Cowan FM, Pennock JM, Hanrahan JD, et al. Early detection of cerebral infarction and hypoxic ischemic encephalopathy in neonates using diffusion-weighted magnetic resonance imaging. Neuropediatrics 1994;25:172–75
    PubMedWeb of Science
  9. Inder T, Huppi PS, Zientara GP, et al. Early detection of periventricular leukomalacia by diffusion-weighted magnetic resonance imaging techniques. J Pediatr 1999;134:631–34
    CrossRefPubMedWeb of Science
  10. ↵
    Liu AY, Zimmerman RA, Haselgrove JC, et al. Diffusion-weighted imaging in the evaluation of watershed hypoxic-ischemic brain injury in pediatric patients. Neuroradiology 2001;43:918–26
    CrossRefPubMed
  11. ↵
    Forbes KP, Pipe JG, Bird R. Neonatal hypoxic-ischemic encephalopathy: detection with diffusion-weighted MR imaging. AJNR Am J Neuroradiol 2000;21:1490–96
    Abstract/FREE Full Text
  12. ↵
    Wolf RL, Zimmerman RA, Clancy R, et al. Quantitative apparent diffusion coefficient measurements in term neonates for early detection of hypoxic-ischemic brain injury: initial experience. Radiology 2001;218:825–33
    PubMedWeb of Science
  13. ↵
    Rutherford M, Counsell S, Allsop J, et al. Diffusion-weighted magnetic resonance imaging in term perinatal brain injury: a comparison with site of lesion and time from birth. Pediatrics 2004;114:1004–14
    Abstract/FREE Full Text
  14. Neil JJ, Shiran SI, McKinstry RC, et al. Normal brain in human newborns: apparent diffusion coefficient and diffusion anisotropy measured by using diffusion tensor MR imaging. Radiology 1998;209:57–66
    PubMedWeb of Science
  15. Lovblad KO, Schneider J, Ruoss K, et al. Isotropic apparent diffusion coefficient mapping of postnatal cerebral development. Neuroradiology 2003;45:400–03
    CrossRefPubMed
  16. ↵
    Tanner SF, Ramenghi LA, Ridgway JP, et al. Quantitative comparison of intrabrain diffusion in adults and preterm and term neonates and infants. AJR Am J Roentgenol 2000;174:1643–49
    PubMedWeb of Science
  17. ↵
    Toft PB, Leth H, Peitersen B, et al. The apparent diffusion coefficient of water in gray and white matter of the infant brain. J Comput Assist Tomogr 1996;20:1006–11
    CrossRefPubMedWeb of Science
  18. ↵
    Barkovich AJ, Westmark KD, Bedi HS, et al. Proton spectroscopy and diffusion imaging on the first day of life after perinatal asphyxia: preliminary report. AJNR Am J Neuroradiol 2001;22:1786–94
    Abstract/FREE Full Text
  19. ↵
    Hunt RW, Neil JJ, Coleman LT, et al. Apparent diffusion coefficient in the posterior limb of the internal capsule predicts outcome after perinatal asphyxia. Pediatrics 2004;114:999–1003
    Abstract/FREE Full Text
  20. ↵
    Vermeulen RJ, Fetter WP, Hendrikx L, et al. Diffusion-weighted MRI in severe neonatal hypoxic ischaemia: the white cerebrum. Neuropediatrics 2003;34:72–76
    CrossRefPubMedWeb of Science
  21. ↵
    Boichot C, Walker PM, Durand C, et al. Term neonate prognoses after perinatal asphyxia: contributions of MR imaging, MR spectroscopy, relaxation times, and apparent diffusion coefficients. Radiology 2006;239:839–48
    CrossRefPubMedWeb of Science
  22. ↵
    Zarifi MK, Astrakas LG, Poussaint TY, et al. Prediction of adverse outcome with cerebral lactate level and apparent diffusion coefficient in infants with perinatal asphyxia. Radiology 2002;225:859–70
    PubMedWeb of Science
  23. ↵
    L'Abee C, de Vries LS, van der Grond J, et al. Early diffusion-weighted MRI and 1H-magnetic resonance spectroscopy in asphyxiated full-term neonates. Biol Neonate 2005;88:306–12
    CrossRefPubMedWeb of Science
  24. ↵
    Liauw L, van der Grond J, van den Berg-Huysmans AA, et al. Hypoxic-ischemic encephalopathy: diagnostic value of conventional MR imaging pulse sequences in term-born neonates. Radiology 2008;247:204–12
    CrossRefPubMedWeb of Science
  25. ↵
    Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress: a clinical and electroencephalographic study. Arch Neurol 1976;33:696–705
    CrossRefPubMedWeb of Science
  26. ↵
    Gesell A, Amatruda CS. Developmental diagnosis: normal and abnormal child development. In: Knobloch HPBH, ed. Developmental Diagnosis; the Evaluation and Management of Normal and Abnormal Neuropsychologic Development in Infancy and Early Childhood. 3rd ed. New York: Harper and Row;1974
  27. ↵
    Brouwers-de Jong EA, Burgmeijer RJF, Laurent de Angulo MS. Ontwikkelingsonderzoek op het consultatiebureau. Handboek bij het vernieuwde Van Wiechenonderzoek. [in Dutch] Assen, the Netherlands: Van Gorcum;1996;1–343
  28. ↵
    Krageloh-Mann I, Helber A, Mader I, et al. Bilateral lesions of thalamus and basal ganglia: origin and outcome. Dev Med Child Neurol 2002;44:477–84
    CrossRefPubMedWeb of Science
  29. Mercuri E, Barnett AL. Neonatal brain MRI and motor outcome at school age in children with neonatal encephalopathy: a review of personal experience. Neural Plast 2003;10:51–57
    PubMed
  30. ↵
    Rutherford M, Srinivasan L, Dyet L, et al. Magnetic resonance imaging in perinatal brain injury: clinical presentation, lesions and outcome. Pediatr Radiol 2006;36:582–92
    CrossRefPubMedWeb of Science
  31. ↵
    Barkovich AJ, Miller SP, Bartha A, et al. MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy. AJNR Am J Neuroradiol 2006;27:533–47
    Abstract/FREE Full Text
  32. ↵
    Mader I, Schoning M, Klose U, et al. Neonatal cerebral infarction diagnosed by diffusion-weighted MRI: pseudonormalization occurs early. Stroke 2002;33:1142–45
    Abstract/FREE Full Text
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American Journal of Neuroradiology: 30 (2)
American Journal of Neuroradiology
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Cite this article
L. Liauw, G. van Wezel-Meijler, S. Veen, M.A. van Buchem, J. van der Grond
Do Apparent Diffusion Coefficient Measurements Predict Outcome in Children with Neonatal Hypoxic-Ischemic Encephalopathy?
American Journal of Neuroradiology Feb 2009, 30 (2) 264-270; DOI: 10.3174/ajnr.A1318

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Do Apparent Diffusion Coefficient Measurements Predict Outcome in Children with Neonatal Hypoxic-Ischemic Encephalopathy?
L. Liauw, G. van Wezel-Meijler, S. Veen, M.A. van Buchem, J. van der Grond
American Journal of Neuroradiology Feb 2009, 30 (2) 264-270; DOI: 10.3174/ajnr.A1318
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