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Research ArticleBrain
Open Access

Brain Structural Variability due to Aging and Gender in Cognitively Healthy Elders: Results from the São Paulo Ageing and Health Study

P.K. Curiati, J.H. Tamashiro, P. Squarzoni, F.L.S. Duran, L.C. Santos, M. Wajngarten, C.C. Leite, H. Vallada, P.R. Menezes, M. Scazufca, G.F. Busatto and T.C.T.F. Alves
American Journal of Neuroradiology November 2009, 30 (10) 1850-1856; DOI: https://doi.org/10.3174/ajnr.A1727
P.K. Curiati
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J.H. Tamashiro
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P. Squarzoni
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F.L.S. Duran
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L.C. Santos
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M. Wajngarten
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C.C. Leite
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H. Vallada
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P.R. Menezes
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M. Scazufca
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G.F. Busatto
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T.C.T.F. Alves
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References

  1. 1.↵
    1. York GK,
    2. Steinberg DA
    . Hughlings Jackson's theory of recovery. Neurology 1995;45:834–38
    Abstract/FREE Full Text
  2. 2.↵
    1. Allen JS,
    2. Bruss J,
    3. Brown CK,
    4. et al
    . Normal neuroanatomical variation due to age: the major lobes and a parcellation of the temporal region. Neurobiol Aging 2005;26:1245–60, discussion 79–82
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Kennedy KM,
    2. Erickson KI,
    3. Rodrigue KM,
    4. et al
    . Age-related differences in regional brain volumes: a comparison of optimized voxel-based morphometry to manual volumetry. Neurobiol Aging 2009;30:1657–76. Epub 2008 Feb 13
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Good CD,
    2. Johnsrude IS,
    3. Ashburner J,
    4. et al
    . A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001;14(1 Pt 1):21–36
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Grieve SM,
    2. Clark CR,
    3. Williams LM,
    4. et al
    . Preservation of limbic and paralimbic structures in aging. Hum Brain Mapp 2005;25:391–401
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Kalpouzos G,
    2. Chetelat G,
    3. Baron JC,
    4. et al
    . Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging. Neurobiol Aging 2009;30:112–24. Epub 2007 Jul 13
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Lemaitre H,
    2. Crivello F,
    3. Grassiot B,
    4. et al
    . Age- and sex-related effects on the neuroanatomy of healthy elderly. Neuroimage 2005;26:900–11
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Terribilli D,
    2. Schaufelberger MS,
    3. Duran FL,
    4. et al
    . Age-related gray matter volume changes in the brain during non-elderly adulthood. Neurobiol Aging 2009 3 10. [Epub ahead of print]
  9. 9.↵
    1. Carne RP,
    2. Vogrin S,
    3. Litewka L,
    4. et al
    . Cerebral cortex: an MRI-based study of volume and variance with age and sex. J Clin Neurosci 2006;13:60–72
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Cowell PE,
    2. Sluming VA,
    3. Wilkinson ID,
    4. et al
    . Effects of sex and age on regional prefrontal brain volume in two human cohorts. Eur J Neurosci 2007;25:307–18
    PubMedWeb of Science
  11. 11.↵
    1. Murphy DG,
    2. DeCarli C,
    3. McIntosh AR,
    4. et al
    . Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch Gen Psychiatry 1996;53:585–94
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Raz N,
    2. Gunning-Dixon F,
    3. Head D,
    4. et al
    . Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume. Neurobiol Aging 2004;25:377–96
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Xu J,
    2. Kobayashi S,
    3. Yamaguchi S,
    4. et al
    . Gender effects on age-related changes in brain structure. AJNR Am J Neuroradiol 2000;21:112–18
    Abstract/FREE Full Text
  14. 14.↵
    1. Nunnemann S,
    2. Wohlschlager AM,
    3. Ilg R,
    4. et al
    . Accelerated aging of the putamen in men but not in women. Neurobiol Aging 2009;30:147–51. Epub 2007 Jul 3
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Benedetti B,
    2. Charil A,
    3. Rovaris M,
    4. et al
    . Influence of aging on brain gray and white matter changes assessed by conventional, MT, and DT MRI. Neurology 2006;66:535–39
    Abstract/FREE Full Text
  16. 16.↵
    1. Sowell ER,
    2. Thompson PM,
    3. Toga AW
    . Mapping changes in the human cortex throughout the span of life. Neuroscientist 2004;10:372–92
    Abstract/FREE Full Text
  17. 17.↵
    1. De Carli D,
    2. Garreffa G,
    3. Colonnese C,
    4. et al
    . Identification of activated regions during a language task. Magn Reson Imaging 2007;25:933–38. Epub 2007 May 23
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Scazufca M,
    2. Menezes PR,
    3. Vallada HP,
    4. et al
    . High prevalence of dementia among older adults from poor socioeconomic backgrounds in Sao Paulo, Brazil. Int Psychogeriatr 2008;20:394–405
    PubMed
  19. 19.↵
    1. Scazufca M,
    2. Seabra CA
    . Sao Paulo portraits: ageing in a large metropolis. Int J Epidemiol 2008;37:721–23. Epub 2007 Jul 31
    FREE Full Text
  20. 20.↵
    1. Prince M,
    2. Ferri CP,
    3. Acosta D,
    4. et al
    . The protocols for the 10/66 dementia research group population-based research programme. BMC Public Health 2007;7:165
    CrossRefPubMed
  21. 21.↵
    1. Wilson PW,
    2. D'Agostino RB,
    3. Levy D,
    4. et al
    . Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837–47
    Abstract/FREE Full Text
  22. 22.
    Diagnostic and Statistical Manual of Mental Disorders (4th edition). Washington, DC: American Psychiatric Association; 1994
  23. 23.↵
    1. Mazziotta JC,
    2. Toga AW,
    3. Evans A,
    4. et al
    . A probabilistic atlas of the human brain: theory and rationale for its development—The International Consortium for Brain Mapping (ICBM). Neuroimage 1995;2:89–101
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Friston KJ,
    2. Holmes AP,
    3. Worsley KJ,
    4. et al
    . Statistic parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 1994;2:189–210
    CrossRef
  25. 25.↵
    1. Brett M,
    2. Johnsrude IS,
    3. Owen AM
    . The problem of functional localization in the human brain. Nat Rev Neurosci 2002;3:243–49
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Riese H
    1. Ey H
    . Hughlings Jackson's fundamental principles applied to psychiatry. Riese H ed. In: Historical Explorations in Medicine and Psychiatry. New York: Springer-Verlag; 1978:204–09
  27. 27.↵
    1. Xu Y,
    2. Valentino DJ,
    3. Scher AI,
    4. et al
    . Age effects on hippocampal structural changes in old men: the HAAS. Neuroimage 2008;40:1003–15. Epub 2007 Dec 27
    CrossRefPubMed
  28. 28.↵
    1. Mosconi L,
    2. De Santi S,
    3. Li J,
    4. et al
    . Hippocampal hypometabolism predicts cognitive decline from normal aging. Neurobiol Aging 2008;29:676–92. Epub 2007 Jan 11
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Smith CD,
    2. Chebrolu H,
    3. Wekstein DR,
    4. et al
    . Age and gender effects on human brain anatomy: a voxel-based morphometric study in healthy elderly. Neurobiol Aging 2007;28:1075–87
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Fujimoto T,
    2. Matsumoto T,
    3. Fujita S,
    4. et al
    . Changes in glucose metabolism due to aging and gender-related differences in the healthy human brain. Psychiatry Res 2008;164:58–72. Epub 2008 Sep 19
    CrossRefPubMed
  31. 31.↵
    1. Keenan PA,
    2. Ezzat WH,
    3. Ginsburg K,
    4. et al
    . Prefrontal cortex as the site of estrogen's effect on cognition. Psychoneuroendocrinology 2001;26:577–90
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Lord C,
    2. Buss C,
    3. Lupien SJ,
    4. et al
    . Hippocampal volumes are larger in postmenopausal women using estrogen therapy compared to past users, never users and men: a possible window of opportunity effect. Neurobiol Aging 2008;29:95–101
    CrossRefPubMedWeb of Science
  33. 33.↵
    1. Taki Y,
    2. Goto R,
    3. Evans A,
    4. et al
    . Voxel-based morphometry of human brain with age and cerebrovascular risk factors. Neurobiol Aging 2004;25:455–63
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 30 (10)
American Journal of Neuroradiology
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P.K. Curiati, J.H. Tamashiro, P. Squarzoni, F.L.S. Duran, L.C. Santos, M. Wajngarten, C.C. Leite, H. Vallada, P.R. Menezes, M. Scazufca, G.F. Busatto, T.C.T.F. Alves
Brain Structural Variability due to Aging and Gender in Cognitively Healthy Elders: Results from the São Paulo Ageing and Health Study
American Journal of Neuroradiology Nov 2009, 30 (10) 1850-1856; DOI: 10.3174/ajnr.A1727

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Brain Structural Variability due to Aging and Gender in Cognitively Healthy Elders: Results from the São Paulo Ageing and Health Study
P.K. Curiati, J.H. Tamashiro, P. Squarzoni, F.L.S. Duran, L.C. Santos, M. Wajngarten, C.C. Leite, H. Vallada, P.R. Menezes, M. Scazufca, G.F. Busatto, T.C.T.F. Alves
American Journal of Neuroradiology Nov 2009, 30 (10) 1850-1856; DOI: 10.3174/ajnr.A1727
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