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OtherPediatric Neuroimaging

Neonatal Alexander Disease: MR Imaging Prenatal Diagnosis

E. Vázquez, A. Macaya, N. Mayolas, S. Arévalo, M.A. Poca and G. Enríquez
American Journal of Neuroradiology November 2008, 29 (10) 1973-1975; DOI: https://doi.org/10.3174/ajnr.A1215
E. Vázquez
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A. Macaya
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N. Mayolas
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S. Arévalo
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M.A. Poca
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G. Enríquez
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References

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    Li R, Johnson AB, Salomons G, et al. Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease. Ann Neurol 2005;57:310–26
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    van der Knaap MS, Valk J. Alexander disease. In: Magnetic Resonance of Myelination and Myelin Disorders. 3rd ed. Berlin, Germany: Springer-Verlag;2005 :416–35
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    Alexander WS. Progressive fibrinoid degeneration of fibrillary astrocytes associated with mental retardation in a hydrocephalic child. Brain 1949;72:373–81
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    Springer S, Erlewein R, Naegele T, et al. Alexander disease: classification revisited and isolation of a neonatal form. Neuropediatrics 2000;31:86–92
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    Herndon RM, Rubinstein LJ, Freeman JM, et al. Light and electron observations on Rosenthal fibers in microscopic Alexander's disease and in multiple sclerosis. J Neuropathol Exp Neurol 1970;30:524–51
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    Dinopoulos A, Gorospe JR, Egelhoff JC, et al. Discrepancy between neuroimaging findings and clinical phenotype in Alexander disease. AJNR Am J Neuroradiol 2006;27:2088–92
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    van der Knaap MS, Naidu S, Breiter SN, et al. Alexander disease: diagnosis with MR imaging. AJNR Am J Neuroradiol 2001;22:541–52
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    Dinopoulos A, Gorospe JR, Egelhoff JC, et al. Molecular findings in symptomatic and pre-symptomatic Alexander disease patients. Neurology 2002;58:1494–500
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    Brenner M, Johnson AB, Boespflug-Tanguy O, et al. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet 2001;27:117–20
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    Rodriguez D, Gauthier F, Bertini E, et al. Infantile Alexander disease: spectrum of GFAP mutations and genotype-phenotype correlation. Am J Hum Genet 2001;69:1134–40
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American Journal of Neuroradiology: 29 (10)
American Journal of Neuroradiology
Vol. 29, Issue 10
November 2008
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Cite this article
E. Vázquez, A. Macaya, N. Mayolas, S. Arévalo, M.A. Poca, G. Enríquez
Neonatal Alexander Disease: MR Imaging Prenatal Diagnosis
American Journal of Neuroradiology Nov 2008, 29 (10) 1973-1975; DOI: 10.3174/ajnr.A1215

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Neonatal Alexander Disease: MR Imaging Prenatal Diagnosis
E. Vázquez, A. Macaya, N. Mayolas, S. Arévalo, M.A. Poca, G. Enríquez
American Journal of Neuroradiology Nov 2008, 29 (10) 1973-1975; DOI: 10.3174/ajnr.A1215
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