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Research ArticlePediatric Neuroimaging

Characterizing Anatomic Differences in Boys with Attention-Deficit/Hyperactivity Disorder with the Use of Deformation-Based Morphometry

J. Wang, T. Jiang, Q. Cao and Y. Wang
American Journal of Neuroradiology March 2007, 28 (3) 543-547;
J. Wang
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T. Jiang
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Q. Cao
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Y. Wang
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    Fig 1.

    Visual summary of the statistical map in which the local volumetric reduction presented statistically significant differences between boys with and without ADHD: left parietal lobe (A), right prefrontal lobe (B), right medial temporal lobe (C), right basal ganglia (especially right putamen) (D).

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    Fig 2.

    Visual summary of the statistical map in which the local volumetric enlargement presented statistically significant differences between boys with and without ADHD: right occipital lobe (A), left posterior lateral ventricle (B).

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  • Summary of the clusters with significant group differences, obtained by voxel-wise statistical analysis of the Jacobian maps of ADHD brains and healthy control brains

    Volume ChangeClusterTalairach Coordinates (x, y, z)Voxel Numbers
    ReductionLeft parietal lobe−32, −61, 41360
    Right prefrontal48, 20, 31407
    Right medial temporal59, −52, 13280
    Right basal ganglia21, 1, 11255
    EnlargementRight occipital lobe20, −86, 29196
    Left posterior lateral ventricle−23, −40, 15302
    • Note:—ADHD indicates attention deficit hyperactivity disorder. Coordinates in Talairach stereotaxic space correspond to local maxima; x, distance (mm) to right (+) or left (−) of the midsagittal line; y, distance anterior (+) or posterior (−) to vertical plane through the anterior commissure; and z, distance above (+) or below (−) the intercommissural (AC-PC) line.

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American Journal of Neuroradiology: 28 (3)
American Journal of Neuroradiology
Vol. 28, Issue 3
March 2007
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J. Wang, T. Jiang, Q. Cao, Y. Wang
Characterizing Anatomic Differences in Boys with Attention-Deficit/Hyperactivity Disorder with the Use of Deformation-Based Morphometry
American Journal of Neuroradiology Mar 2007, 28 (3) 543-547;

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Characterizing Anatomic Differences in Boys with Attention-Deficit/Hyperactivity Disorder with the Use of Deformation-Based Morphometry
J. Wang, T. Jiang, Q. Cao, Y. Wang
American Journal of Neuroradiology Mar 2007, 28 (3) 543-547;
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