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Research ArticleBrain

Brain MRI in Neurodegeneration with Brain Iron Accumulation with and without PANK2 Mutations

S.J. Hayflick, M. Hartman, J. Coryell, J. Gitschier and H. Rowley
American Journal of Neuroradiology June 2006, 27 (6) 1230-1233;
S.J. Hayflick
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M. Hartman
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J. Coryell
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J. Gitschier
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H. Rowley
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References

  1. ↵
    Tanfani G, Mascalchi M, Dal Pozzo G, et al. MR imaging in a case of Hallervorden-Spatz disease. J Comput Assist Tomogr 1987;11:1057–58.
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    Sethi KD, Adams RJ, Loring DW, et al. Hallervorden-Spatz syndrome: clinical and magnetic resonance imaging correlations. Ann Neurol 1988;24:692–94
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    Hayflick SJ, Westaway SK, Levinson B, et al. Genetic, clinical and radiographic delineation of Hallervorden-Spatz syndrome. N Engl J Med 2003;348:33–40
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    Zhou B, Westaway SK, Levinson B, et al. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat Genet 2001;28:345–49
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    Hayflick SJ, Penzien JM, Michl W, et al. Cranial MRI changes may precede symptoms in Hallervorden-Spatz syndrome. Pediatr Neurol 2001;25:166–69
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    Hallervorden J, Spatz H. Eigenartige Erkrankung im extrapyramidalen System mit besonderer Beteiligung des Globus pallidus und der Substantia nigra. Z Ges Neurol Psychiatr 1922;79:254–302
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    Swaiman KF. Hallervorden-Spatz syndrome and brain iron metabolism. Arch Neurol 1991;48:1285–93
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 27 (6)
American Journal of Neuroradiology
Vol. 27, Issue 6
June 2006
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Cite this article
S.J. Hayflick, M. Hartman, J. Coryell, J. Gitschier, H. Rowley
Brain MRI in Neurodegeneration with Brain Iron Accumulation with and without PANK2 Mutations
American Journal of Neuroradiology Jun 2006, 27 (6) 1230-1233;

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Brain MRI in Neurodegeneration with Brain Iron Accumulation with and without PANK2 Mutations
S.J. Hayflick, M. Hartman, J. Coryell, J. Gitschier, H. Rowley
American Journal of Neuroradiology Jun 2006, 27 (6) 1230-1233;
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  • Looking Deep into the Eye-of-the-Tiger in Pantothenate Kinase-Associated Neurodegeneration
  • Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration
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  • Depression in patients with Huntington disease correlates with alterations of the brain stem raphe depicted by transcranial sonography
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