Research ArticleSpine Imaging and Spine Image-Guided Interventions
Diffusion Tensor Imaging in Multiple Sclerosis: Assessment of Regional Differences in the Axial Plane within Normal-Appearing Cervical Spinal Cord
S.M. Hesseltine, M. Law, J. Babb, M. Rad, S. Lopez, Y. Ge, G. Johnson and R.I. Grossman
American Journal of Neuroradiology June 2006, 27 (6) 1189-1193;
S.M. Hesseltine
M. Law
J. Babb
M. Rad
S. Lopez
Y. Ge
G. Johnson

References
- ↵Lin X, Tench CR, Turner B, et al. Spinal cord atrophy and disability in multiple sclerosis over four years: application of a reproducible automated technique in monitoring disease progression in a cohort of the interferon {beta}-1a (Rebif) treatment trial. J Neurol Neurosurg Psychiatry 2003;74:1090–94
- ↵Losseff N, Webb S, O’Riordan J, et al. Spinal cord atrophy and disability in multiple sclerosis. A new reproducible and sensitive MRI method with potential to monitor disease progression. Brain 1996;119:701–08
- ↵Schwartz ED, Cooper ET, Chin C-L, et al. Ex vivo evaluation of ADC values within spinal cord white matter tracts. AJNR Am J Neuroradiol 2005;26:390–97
- ↵Valsasina P, Rocca MA, Agosta F, et al. Mean diffusivity and fractional anisotropy histogram analysis of the cervical cord in MS patients. NeuroImage 2005;26:822–28
- ↵Agosta F, Benedetti B, Rocca MA, et al. Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI. Neurology 2005;64:631–35
- ↵Thielen KR, Miller GM. Multiple sclerosis of the spinal cord: magnetic resonance appearance. J Comput Assist Tomogr 1996;20:434–38
- ↵McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol 2001;50:121–27
- ↵Miller DH, Barkhof F, Frank JA, et al. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain 2002;125:1676–95
- De Stefano N, Matthews PM, Filippi M, et al. Evidence of early cortical atrophy in MS: relevance to white matter changes and disability. Neurology 2003;60:1157–62
- ↵Sailer M, Fischl B, Salat D, et al. Focal thinning of the cerebral cortex in multiple sclerosis. Brain 2003;126:1734–44
- ↵Law M, Saindane AM, Ge Y, et al. Microvascular abnormality in relapsing-remitting multiple sclerosis: perfusion MR imaging findings in normal-appearing white matter. Radiology 2004;231:645–52
- Davie CA, Barker GJ, Thompson AJ, et al. 1H magnetic resonance spectroscopy of chronic cerebral white matter lesions and normal appearing white matter in multiple sclerosis. J Neurol Neurosurg Psychiatry 1997;63:736–42
- Husted CA, Goodin DS, Hugg JW, et al. Biochemical alterations in multiple sclerosis lesions and normal-appearing white matter detected by in vivo 31P and 1H spectroscopic imaging. Ann Neurol 1994;36:157–65
- Filippi M, Rocca MA, Minicucci L, et al. Magnetization transfer imaging of patients with definite MS and negative conventional MRI. Neurology 1999;52:845–48
- Ge Y, Law M, Johnson G, et al. Preferential occult injury of corpus callosum in multiple sclerosis measured by diffusion tensor imaging. J Magn Reson Imaging 2004;20:1–7
- Wilson M, Tench CR, Morgan PS, et al. Pyramidal tract mapping by diffusion tensor magnetic resonance imaging in multiple sclerosis: improving correlations with disability. J Neurol Neurosurg Psychiatry 2003;74:203–07
- Loevner LA, Grossman RI, Cohen JA, et al. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196:511–15
- ↵Inglese M, Ge Y, Filippi M, et al. Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis. NeuroImage 2004;21:1825–29
- ↵Bot JCJ, Blezer ELA, Kamphorst W, et al. The spinal cord in multiple sclerosis: relationship of high-spatial-resolution quantitative MR imaging findings to histopathologic results. Radiology 2004;233:531–40
- ↵Clark CA, Werring DJ, Miller DH. Diffusion imaging of the spinal cord in vivo: estimation of the principal diffusivities and application to multiple sclerosis. Magn Reson Med 2000;43:133–38
- ↵Tsuchiya K, Katase S, Fujikawa A, et al. Diffusion-weighted MRI of the cervical spinal cord using a single-shot fast spin-echo technique: findings in normal subjects and in myelomalacia. Neuroradiology 2003;45:90–94
- ↵
- ↵Evangelou N, DeLuca GC, Owens T, et al. Pathological study of spinal cord atrophy in multiple sclerosis suggests limited role of local lesions. Brain 2005;128:29–34
- ↵Bergers E, Bot JCJ, De Groot CJA, et al. Axonal damage in the spinal cord of MS patients occurs largely independent of T2 MRI lesions. Neurology 2002;59:1766–71
- ↵Tsuchiya K, Fujikawa A, Suzuki Y. Diffusion tractography of the cervical spinal cord by using parallel imaging. AJNR Am J Neuroradiol 2005;26:398–400
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S.M. Hesseltine, M. Law, J. Babb, M. Rad, S. Lopez, Y. Ge, G. Johnson, R.I. Grossman
Diffusion Tensor Imaging in Multiple Sclerosis: Assessment of Regional Differences in the Axial Plane within Normal-Appearing Cervical Spinal Cord
American Journal of Neuroradiology Jun 2006, 27 (6) 1189-1193;
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