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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleHead and Neck Imaging

OK-432 Sclerotherapy of Plunging Ranula in 21 Patients: It Can Be a Substitute for Surgery

M.H. Rho, D.W. Kim, J.S. Kwon, S.W. Lee, Y.S. Sung, Y.K. Song, M.G. Kim and S.G. Kim
American Journal of Neuroradiology May 2006, 27 (5) 1090-1095;
M.H. Rho
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D.W. Kim
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J.S. Kwon
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S.W. Lee
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Y.S. Sung
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Y.K. Song
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M.G. Kim
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S.G. Kim
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Article Figures & Data

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  • Fig 1.
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    Fig 1.

    Case 18. A 29-year-old man with severe left submandibular swelling shows total shrinkage after a single OK-432 injection.

    A and B, Initial contrast-enhanced CT scan shows a large plunging ranula in the left sublingual (arrows) and submandibular spaces (arrowheads) with extending to the upper neck.

    C and D, Follow-up postcontrast CT scan obtained 6 months after OK-432 sclerotherapy depicts total shrinkage of the plunging ranula.

  • Fig 2.
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    Fig 2.

    Case 1. A 21-year-old woman with a slow-growing mass in the right sublingual area shows near-total shrinkage after a single OK-432 injection.

    A, Contrast-enhanced CT scan shows a large cystic lesion (arrows) in the right submandibular space.

    B, Follow-up CT scan obtained 2 months after OK-432 sclerotherapy shows nearly total shrinkage of the plunging ranula (arrows).

    C, Follow-up sonogram obtained 43 months after OK-432 sclerotherapy shows 2 small residual cystic lesions (arrows) in the right submandibular space. They represent less than 5% of the original volume of the cyst.

  • Fig 3.
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    Fig 3.

    Case 2. A 24-year-old man with tender swelling in the right submandibular area shows marked shrinkage after 2 OK-432 injections.

    A, Contrast-enhanced CT scan shows a plunging ranula in the right submandibular space (arrows).

    B, Contrast-enhanced CT scan obtained 2 months after the first sclerotherapy shows near total shrinkage of the plunging ranula (arrow), but the 3-month follow-up sonogram showed enlargement of the cyst.

    C, Unenhanced CT scan obtained 3 years after the second injection shows marked shrinkage of the cyst (which was larger than after first injection) (arrow).

  • Fig 4.
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    Fig 4.

    Case 3. A 10-year-old boy with sublingual swelling shows partial shrinkage after 3 OK-432 injections.

    A and B, The initial contrast-enhanced CT scan shows cystic lesions in the right sublingual space (arrows) and submental space (arrowheads).

    C and D, Unenhanced CT scan taken 2 months after the first sclerotherapy, depicts disappearance of the cyst in the right sublingual space (arrow), but a cyst remains in the submental space (arrowheads). The ranula in the submental space recurred after its complete shrinkage after the next 2 OK-432 injections.

  • Fig 5.
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    Fig 5.

    Case 13. A 20-year-old man with tender swelling in the left submandibular area.

    A and B, Initial enhanced CT scan shows multilocular, rim-enhancing cystic lesions in the right sublingual and submandibular space (arrows) with adjacent soft tissue infiltration and swelling (arrowheads). This abscess-like lesion was drained by pigtail catheter for 5 days. OK-432 sclerotherapy was performed 10 days after the pigtail catheter drainage of the plunging ranula.

    C and D, Follow-up transverse and longitudinal sonograms obtained 11 months after OK-432 sclerotherapy shows complete shrinkage of the cystic lesion in the right sublingual space (arrowheads) and submandibular space (arrows).

Tables

  • Figures
  • Results of the OK-432 sclerotherapy of plunging ranula

    Patient No./Age (y)/SexLocationAspiration(cc)Injection(cc)No. of SclerotherapiesDuration of Follow-up (mo)Result
    1/21/FRight sublingual1210143Near total
    2/24/MRight submandibular6723Recurred
    3536Marked
    3/10/MLeft sublingual and submandibular7732Partial
    667Partial
    9926Partial
    4/10/MRight submandibular44110Total
    5/19/MLeft submandibular7753Recurred
    553Recurred
    447Recurred
    6819Recurred
    776Partial
    6/10/FSublingual and left submandibular121019Total
    7/28/MSubmental5537Recurred
    664Recurred
    10108Recurred
    8/41/MLeft submandibular9831Recurred
    463Recurred
    5630Marked
    9/28/FSubmental9921Recurred
    992Recurred
    10/39/MLeft submental and sublingual3020130Marked
    11/16/MLeft submandibular1717129Total
    12/7/FLeft submental1110113Total
    13/20/MRight Submandibular27111Total
    14/22/MLeft submandibular261019Near total
    15/19/FRight submandibular4517Recurred
    16/7/FLeft submental1123Recurred
    776Marked
    17/14/FRight submandibular231016Partial
    18/29/MLeft submandibular222016Total
    19/25/MRight submandibular and cheek313016Near total
    20/16/MLeft submandibular7716Total
    21/31/FRight submandibular161616Near total
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American Journal of Neuroradiology: 27 (5)
American Journal of Neuroradiology
Vol. 27, Issue 5
May 2006
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Cite this article
M.H. Rho, D.W. Kim, J.S. Kwon, S.W. Lee, Y.S. Sung, Y.K. Song, M.G. Kim, S.G. Kim
OK-432 Sclerotherapy of Plunging Ranula in 21 Patients: It Can Be a Substitute for Surgery
American Journal of Neuroradiology May 2006, 27 (5) 1090-1095;

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OK-432 Sclerotherapy of Plunging Ranula in 21 Patients: It Can Be a Substitute for Surgery
M.H. Rho, D.W. Kim, J.S. Kwon, S.W. Lee, Y.S. Sung, Y.K. Song, M.G. Kim, S.G. Kim
American Journal of Neuroradiology May 2006, 27 (5) 1090-1095;
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