Article Figures & Data
Figures
- Fig 1.
Case 18. A 29-year-old man with severe left submandibular swelling shows total shrinkage after a single OK-432 injection.
A and B, Initial contrast-enhanced CT scan shows a large plunging ranula in the left sublingual (arrows) and submandibular spaces (arrowheads) with extending to the upper neck.
C and D, Follow-up postcontrast CT scan obtained 6 months after OK-432 sclerotherapy depicts total shrinkage of the plunging ranula.
- Fig 2.
Case 1. A 21-year-old woman with a slow-growing mass in the right sublingual area shows near-total shrinkage after a single OK-432 injection.
A, Contrast-enhanced CT scan shows a large cystic lesion (arrows) in the right submandibular space.
B, Follow-up CT scan obtained 2 months after OK-432 sclerotherapy shows nearly total shrinkage of the plunging ranula (arrows).
C, Follow-up sonogram obtained 43 months after OK-432 sclerotherapy shows 2 small residual cystic lesions (arrows) in the right submandibular space. They represent less than 5% of the original volume of the cyst.
- Fig 3.
Case 2. A 24-year-old man with tender swelling in the right submandibular area shows marked shrinkage after 2 OK-432 injections.
A, Contrast-enhanced CT scan shows a plunging ranula in the right submandibular space (arrows).
B, Contrast-enhanced CT scan obtained 2 months after the first sclerotherapy shows near total shrinkage of the plunging ranula (arrow), but the 3-month follow-up sonogram showed enlargement of the cyst.
C, Unenhanced CT scan obtained 3 years after the second injection shows marked shrinkage of the cyst (which was larger than after first injection) (arrow).
- Fig 4.
Case 3. A 10-year-old boy with sublingual swelling shows partial shrinkage after 3 OK-432 injections.
A and B, The initial contrast-enhanced CT scan shows cystic lesions in the right sublingual space (arrows) and submental space (arrowheads).
C and D, Unenhanced CT scan taken 2 months after the first sclerotherapy, depicts disappearance of the cyst in the right sublingual space (arrow), but a cyst remains in the submental space (arrowheads). The ranula in the submental space recurred after its complete shrinkage after the next 2 OK-432 injections.
- Fig 5.
Case 13. A 20-year-old man with tender swelling in the left submandibular area.
A and B, Initial enhanced CT scan shows multilocular, rim-enhancing cystic lesions in the right sublingual and submandibular space (arrows) with adjacent soft tissue infiltration and swelling (arrowheads). This abscess-like lesion was drained by pigtail catheter for 5 days. OK-432 sclerotherapy was performed 10 days after the pigtail catheter drainage of the plunging ranula.
C and D, Follow-up transverse and longitudinal sonograms obtained 11 months after OK-432 sclerotherapy shows complete shrinkage of the cystic lesion in the right sublingual space (arrowheads) and submandibular space (arrows).
Tables
Results of the OK-432 sclerotherapy of plunging ranula
Patient No./Age (y)/Sex Location Aspiration(cc) Injection(cc) No. of Sclerotherapies Duration of Follow-up (mo) Result 1/21/F Right sublingual 12 10 1 43 Near total 2/24/M Right submandibular 6 7 2 3 Recurred 3 5 36 Marked 3/10/M Left sublingual and submandibular 7 7 3 2 Partial 6 6 7 Partial 9 9 26 Partial 4/10/M Right submandibular 4 4 1 10 Total 5/19/M Left submandibular 7 7 5 3 Recurred 5 5 3 Recurred 4 4 7 Recurred 6 8 19 Recurred 7 7 6 Partial 6/10/F Sublingual and left submandibular 12 10 1 9 Total 7/28/M Submental 5 5 3 7 Recurred 6 6 4 Recurred 10 10 8 Recurred 8/41/M Left submandibular 9 8 3 1 Recurred 4 6 3 Recurred 5 6 30 Marked 9/28/F Submental 9 9 2 1 Recurred 9 9 2 Recurred 10/39/M Left submental and sublingual 30 20 1 30 Marked 11/16/M Left submandibular 17 17 1 29 Total 12/7/F Left submental 11 10 1 13 Total 13/20/M Right Submandibular 2 7 1 11 Total 14/22/M Left submandibular 26 10 1 9 Near total 15/19/F Right submandibular 4 5 1 7 Recurred 16/7/F Left submental 1 1 2 3 Recurred 7 7 6 Marked 17/14/F Right submandibular 23 10 1 6 Partial 18/29/M Left submandibular 22 20 1 6 Total 19/25/M Right submandibular and cheek 31 30 1 6 Near total 20/16/M Left submandibular 7 7 1 6 Total 21/31/F Right submandibular 16 16 1 6 Near total
