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OtherBrain

MR Diffusion Tensor Imaging, Fiber Tracking, and Single-Voxel Spectroscopy Findings in an Unusual MELAS Case

Denis Ducreux, Ghaidaa Nasser, Catherine Lacroix, David Adams and Pierre Lasjaunias
American Journal of Neuroradiology August 2005, 26 (7) 1840-1844;
Denis Ducreux
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Ghaidaa Nasser
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Catherine Lacroix
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David Adams
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Pierre Lasjaunias
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    Fig 1.

    Axial fluid-attenuated inversion recovery MR (A) and diffusion-weighted b0 (B) images show an abnormal area in the right mesencephalon (arrows). Apparent diffusion coefficient (C) and fractional anisotropy (D) color-scale parametric maps show an increased apparent diffusion coefficient and decreased fractional anisotropy values (green) in the same abnormal area (B) (arrowheads).

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    Fig 2.

    Spinal cord sagittal T2-weighted MR (A) and diffusion-weighted b0 (B) images show wide intraspinal abnormal areas (arrows). Apparent diffusion coefficient (C) and fractional anisotropy (D) color-scale parametric maps show increased apparent diffusion coefficient and decreased fractional anisotropy values (green) in the same abnormal area (arrowheads).

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    Fig 3.

    Spinal cord sagittal T2-weighted MR (A) and diffusion-weighted b0 (B) images show wide intraspinal abnormal areas (arrows). Fiber tracking (C), coregistered and projected on a T2-weighted image, shows an unexpected unaltered shape of the white matter tracts, with visualization (D) of corticospinal tracts and nerve roots (arrowhead).

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    Fig 4.

    Sagittal T2-weighted MR image (A) shows extensive abnormal areas involving the brain stem and the cervical spinal cord (arrow). A long TE MR spectroscopy voxel was located on fluid-attenuated inversion recovery abnormal areas in the medulla oblongata (B, arrow) and showed a spectrum with increased Cho peak, decreased NAA peak, and an inverted 1.3-ppm lactate peak (Lac, arrow box). Cr indicates creatine.

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American Journal of Neuroradiology: 26 (7)
American Journal of Neuroradiology
Vol. 26, Issue 7
1 Aug 2005
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Denis Ducreux, Ghaidaa Nasser, Catherine Lacroix, David Adams, Pierre Lasjaunias
MR Diffusion Tensor Imaging, Fiber Tracking, and Single-Voxel Spectroscopy Findings in an Unusual MELAS Case
American Journal of Neuroradiology Aug 2005, 26 (7) 1840-1844;

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MR Diffusion Tensor Imaging, Fiber Tracking, and Single-Voxel Spectroscopy Findings in an Unusual MELAS Case
Denis Ducreux, Ghaidaa Nasser, Catherine Lacroix, David Adams, Pierre Lasjaunias
American Journal of Neuroradiology Aug 2005, 26 (7) 1840-1844;
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