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Research ArticleINTERVENTIONAL

Emergency Carotid Artery Stent Placement in Patients with Acute Ischemic Stroke

Keisuke Imai, Takahisa Mori, Hajime Izumoto, Masaki Watanabe and Kenichiro Majima
American Journal of Neuroradiology May 2005, 26 (5) 1249-1258;
Keisuke Imai
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Takahisa Mori
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Hajime Izumoto
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Masaki Watanabe
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Kenichiro Majima
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  • Fig 1.
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    Fig 1.

    Images obtained on admission in case 1.

    A, DW image reveals slightly high signal intensity in the cortex of the left parietal lobe.

    B, The rMTT map of PW image shows delay of 15–25% in the territory of the left MCA (ROI 2 and 4).

    C, The rCBV map of PW image shows slight decrease of 2–12% in the territory of the left MCA (ROI 2 and 4).

    D, The rCBF map of PW image reveals reduction of 11–23% in the territory of the left MCA (ROI 2 and 4).

    E, MR angiogram shows poor visualization of the left ICA.

  • Fig 2.
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    Fig 2.

    Periprocedural images obtained in case 1.

    A, Lateral left carotid angiogram obtained before the procedure shows severe stenosis at the origin of the ICA.

    B, Lateral left carotid angiogram obtained during the procedure demonstrates stent implantation and postdilation.

    C, Lateral left carotid angiogram obtained after the procedure shows an excellent angiographic result.

  • Fig 3.
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    Fig 3.

    Images obtained on admission in case 4.

    A, DW image reveals no area of high signal intensity in the left cerebral hemisphere.

    B, The rMTT map of PW image shows delay of 15% in the territory of the left MCA (ROI 4).

    C, The rCBV map of PW image shows slight decrease of 11.2% in the territory of the left MCA (ROI 4).

    D, The rCBF map of PW image reveals reduction of 43% in the territory of the left MCA (ROI 4).

    E, MR angiogram shows no visualization of the left ICA.

  • Fig 4.
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    Fig 4.

    Periprocedural angiograms obtained in case 4.

    A, Lateral left carotid angiogram obtained before the procedure shows occlusion at the origin of the ICA.

    B, Lateral left carotid angiogram obtained during the procedure demonstrates stent implantation and postdilation.

    C, Lateral left carotid angiogram obtained after the procedure shows essentially complete recanalization with 14% residual stenosis of the ICA.

  • Fig 5.
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    Fig 5.

    NIHSS scores at 7 days after emergency carotid stent placement (symbols on right) improved significantly (P < .01) compared with baseline scores (symbols on left). W indicates Wilcoxon rank sum test; •, patients with sudden onset of severe stroke; ▴, patients with progressing stroke.

Tables

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    TABLE 1:

    Patient characteristics and clinical information before emergency carotid artery stent placement

    Case No./Sex/Age (y)Type of StrokeClinical SymptomsNIHSS ScoreTreatmentOnset to Procedure (hrs)
    1/F/83SODeep coma, CD, QP28Aspirin, ticlopidine2
    2/M/65SOSomnolence, MA, FP, HP9Aspirin10
    3/M/69SOComa, CD, HP19None24
    4/M/60SOComa, HP18None8
    5/M/68SOSomnolence, HP7Aspirin12
    6/M/28SOSomnolence, FP, HP13None2
    7/M/78SOStupor, AG, CD, FP, HP15None17
    8/M/83SOSomnolence, FP, HP12Aspirin18
    9/M/66SOSomnolence, FP, HP11None6
    10/F/86PRSomnolence, SA, HP12Heparin125
    11/M/69PRSomnolence, AG, HP11Heparin, ozagrel sodium72
    12/M/68PRAG, HP5Heparin, ozagrel sodium149
    13/F/74PRStupor, AG, FP, HP15Argatroban54
    14/F/69PRSomnolence, FP, HP7Argatroban, aspirin120
    15/M/82PRComa, CD, HP24Heparin26
    16/M/62PRFP, HP5Heparin, aspirin120
    17/M/79PRFP, HP5Argatroban, ticlopidine168
    • Note.—SO indicates sudden onset of severe stroke; PR, progressing stroke; CD, conjugate deviation of the eyes; QP, quadriparesis; MA, motor-dominant aphasia; FP, facial palsy; HP, hemiplegia or hemiparesis; AG, agnosia; SA, sensory-dominant aphasia.

    • View popup
    TABLE 2:

    Preprocedure MR findings

    Case No./Sex/Age (y)Side of LesionArea of High Signal IntensityDW ImagingPW ImagingPerfusion-Diffusion Mismatch
    rMTTrCBVrCBF
    1/F/83LCPSmall abnormalityDelaySmall decreaseSmall reductionSmall
    2/M/65LDBZ, CFSmall abnormalityDelaySmall decreaseSmall reductionSmall
    3/M/69LBGSmall abnormalityDelayLarge decreaseLarge reductionLarge
    4/M/60LNoneNormalDelayLarge decreaseLarge reductionLarge
    5/M/68RNoneNormalDelayLarge decreaseLarge reductionLarge
    6/M/28RDBZ, CFSmall abnormalityDelayLarge decreaseLarge reductionLarge
    7/M/78RSBZ, CFSmall abnormalityDelaySmall decreaseSmall reductionSmall
    8/M/83RNoneNormalDelayLarge decreaseLarge reductionLarge
    9/M/66RDBZ, CFSmall abnormalityDelayLarge decreaseLarge reductionLarge
    10/F/86LSBZ, DBZSmall abnormalityDelayLarge decreaseLarge reductionLarge
    11/M/69RDBZ, CPSmall abnormalityDelaySmall decreaseSmall reductionSmall
    12/M/68RSBZSmall abnormalityDelaySmall decreaseSmall reduction*Small
    13/F/74RDBZ, CFSmall abnormalityDelaySmall decreaseSmall reductionSmall
    14/F/69LDBZSmall abnormalityDelaySmall decreaseSmall reductionSmall
    15/M/82LCFSmall abnormalityDelaySmall decreaseSmall reductionSmall
    16/M/62LDBZSmall abnormalityDelayLarge decreaseLarge reductionLarge
    17/M/79RDBZSmall abnormalityDelaySmall decreaseSmall reductionSmall
    • Note.—CP indicates cortex of the parietal lobe; DBZ, deep border zone; CF, cortex of the frontal lobe; BG, basal ganglia; SBZ, superficial border zone.

    • * Contralateral ICA stenosis.

    • View popup
    TABLE 3:

    Preprocedure angiographic findings and devices used for emergency carotid artery stent placement

    Case No./Sex/Age (y)Preprocedure Stenosis (%)Cause of LesionStent DevicesProtection Technique
    1/F/8399AtherothromboticS670No
    2/M/6599AtherothromboticS670No
    3/M/6994AtherothromboticNIR EliteNo
    4/M/60100AtherothromboticS670No
    5/M/6893AtherothromboticS670No
    6/M/28100DissectionEasy WallstentNo
    7/M/7899AtherothromboticNIR EliteNo
    8/M/83100AtherothromboticEasy WallstentYes
    9/M/6699AtherothromboticEasy WallstentYes
    10/F/86100AtherothromboticS670No
    11/M/6995AtherothromboticS670No
    12/M/6875AtherothromboticNIR EliteNo
    13/F/7499AtherothromboticS670No
    14/F/6999AtherothromboticNIR EliteNo
    15/M/8270AtherothromboticEasy WallstentNo
    16/M/6295AtherothromboticEasy WallstentNo
    17/M/7975AtherothromboticEasy WallstentNo
    • View popup
    TABLE 4:

    Postprocedure findings

    Case No./Sex/Age (y)Postprocedure Stenosis (%)*Stenosis at 90 days (%)*HP at SPECTCT Findings within 24 hrs after Procedure
    1/F/83520NegativeSLA
    2/M/651020NegativeSLA
    3/M/691212NegativeSLA
    4/M/601440PositiveNLA + SAH
    5/M/6800PositiveNLA
    6/M/2888NegativeLLA
    7/M/781220NegativeLLA
    8/M/8355NegativeSLA
    9/M/66150PositiveSLA
    10/F/8620No evaluationPositiveSLA + SAH
    11/M/690No evaluationNegativeSLA
    12/M/68010NegativeSLA
    13/F/741820NegativeSLA
    14/F/6988NegativeNLA
    15/M/8210No evaluationNegativeSLA
    16/M/6280NegativeSLA
    17/M/790No evaluationNegativeSLA
    • Note.—HP indicates hyperperfusion phenomenon; SLA, small low-attenuation area; LLA, large low-attenuation area; NLA, no low-attenuation area; SAH, subarachnoid hemorrhage.

    • * * Evaluation by angiography.

    • View popup
    TABLE 5:

    Clinical results

    Case No./Sex/Age (y)NIHSS ScoremRS Score at 90 Days after ProcedureProcedure-Related Complications
    On AdmissionJust Before ProcedureAt 7 Days after Procedure
    1/F/83282831Hypotension, bradycardia
    2/M/659900None
    3/M/691919144None
    4/M/60181810Hypertension
    5/M/687740Hypotension, bradycardia
    6/M/28131393None
    7/M/781515134Hypertension, distal embolism
    8/M/83121251Hypertension
    9/M/66111151Hypertension
    10/F/86412154Hypertension
    11/M/6911*1122Hypotension, bradycardia
    12/M/682500None
    13/F/7415*1591None
    14/F/694700None
    15/M/82324246None
    16/M/6215153Putaminal hemorrhage
    17/M/792530Hypotension, bradycardia
    • * Scores of patients transferred from another hospital.

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American Journal of Neuroradiology: 26 (5)
American Journal of Neuroradiology
Vol. 26, Issue 5
1 May 2005
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Cite this article
Keisuke Imai, Takahisa Mori, Hajime Izumoto, Masaki Watanabe, Kenichiro Majima
Emergency Carotid Artery Stent Placement in Patients with Acute Ischemic Stroke
American Journal of Neuroradiology May 2005, 26 (5) 1249-1258;

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Emergency Carotid Artery Stent Placement in Patients with Acute Ischemic Stroke
Keisuke Imai, Takahisa Mori, Hajime Izumoto, Masaki Watanabe, Kenichiro Majima
American Journal of Neuroradiology May 2005, 26 (5) 1249-1258;
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  • Antithrombotic regimen in emergent carotid stenting for acute ischemic stroke due to tandem occlusion: a meta-analysis of aggregate data
  • Endovascular treatment in patients with acute ischemic stroke and apparent occlusion of the extracranial internal carotid artery on CTA
  • Emergency carotid artery stenting in patients with acute ischemic stroke due to occlusion or stenosis of the proximal internal carotid artery: a single-center experience
  • Forced suction thrombectomy after carotid stenting in patients with massive thrombus and acute extracranial internal carotid artery occlusion
  • Predictors of Functional Outcome after Emergency Carotid Artery Stenting and Intra-Arterial Thrombolysis for Treatment of Acute Stroke Associated with Obstruction of the Proximal Internal Carotid Artery and Tandem Downstream Occlusion
  • Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
  • Safety and effectiveness of emergency carotid artery stenting for a high-grade carotid stenosis with intraluminal thrombus under proximal flow control in hyperacute and acute stroke
  • Multimodal Reperfusion Therapy for Large Hemispheric Infarcts in Octogenarians: Is Good Outcome a Realistic Goal?
  • Carotid Artery Stenting in Acute Stroke
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More in this TOC Section

  • Safety, Efficacy, and Durability of Stent-Assisted Coiling Treatment of M2 (Insular) Segment MCA Aneurysms
  • Endovascular Management of Intracranial Dural AVFs: Transvenous Approach
  • A Meta-analysis of Combined Aspiration Catheter and Stent Retriever versus Stent Retriever Alone for Large-Vessel Occlusion Ischemic Stroke
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