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Tumefactive Cysts: A Delayed Complication following Radiosurgery for Cerebral Arterial Venous Malformations

Whitney B. Edmister, John I. Lane, Julie R. Gilbertson, Robert D. Brown and Bruce E. Pollock
American Journal of Neuroradiology May 2005, 26 (5) 1152-1157;
Whitney B. Edmister
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John I. Lane
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Julie R. Gilbertson
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Robert D. Brown
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Bruce E. Pollock
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  • Fig 1.
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    Fig 1.

    Radiation therapy-induced cyst 89 months after AVM treatment.

    A, T2-weighted axial image shows a 3-cm cyst in the frontoparietal region with vasogenic edema (arrow).

    B, Contrast-enhanced T1-weighted axial image shows nodular contrast enhancement superficial to the cyst (arrow).

    C, Postoperative CT showed successful cyst decompression (arrow) after cystoperitoneal shunt placement.

  • Fig 2.
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    Fig 2.

    MR image obtained 40 months after AVM ablation.

    A, T2-weighted axial image showed a 5-cm complex, multiloculated cyst in the left frontoparietal region with vasogenic edema and local mass effect (arrow).

    B, Contrast-enhanced T1-weighted axial image shows nodular parenchymal enhancement (arrow).

    C, CT after successful cystoperitoneal shunt placement shows decompression of the cysts.

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    Fig 3.

    MR image obtained 34 months after AVM ablation.

    A, T2-weighted axial image shows multiple complex cysts in the posterior right temporal, occipital, and parietal region with vasogenic edema and mass effect.

    B, Contrast-enhanced T1-weighted axial image shows nodular parenchymal enhancement.

    C and D, MR images obtained after successful cystoperitoneal placement. Vasogenic edema and enhancement persist, but the patient remains asymptomatic after 4 years.

  • Fig 4.
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    Fig 4.

    MR image obtained 59 months after AVM ablation.

    A, T2-weighted axial image demonstrates multilocular cyst with surrounding vasogenic edema (arrow).

    B, Contrast-enhanced T1-weighted axial image shows nodular parenchymal enhancement (arrow).

    C and D, MR after cystectomy show postoperative encephalomalacia, resolution of cysts and minimal residual parenchymal enhancement (arrow).

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    Fig 5.

    MR image obtained 36 months after AVM ablation.

    A, Contrast-enhanced axial T1-weighted image shows a peripherally enhancing, multiloculated cyst in the left parietal lobe.

    B and C, T2-weighted and post-contrast T1-weighted images obtained after cystoperitoneal shunting show residual cyst and enhancement (arrows).

Tables

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  • Summary of patient demographics and clinical history

    CaseAge at Gamm a TxSexRx isodose vol (cc), margin/max dose (Gy)Tx to cyst Dx (months)Size at Dx (cc)SxTxAVM location
    133F28.7, 16/208914.0HA, L arm weakness.Aspiration; CP shunt.R parietal
    223F13.4, 16/32661.0 (40 at 106 months)None. HA, mild aphasia, transient R arm paresthesia at 106 months.Aspiration; CP shunt.L parietal
    320F13.5, 28/22.53411.9HA.Aspiration; CP shunt.R temporal
    456F8.0, 16/32 4.9, 18/36594.0Repeat Tx at 44 months. HA, ataxia.Aspiration; CP shunt; cystectomy.R temporal
    524M11.1, 18/36 16.5, 16/32373.5 (63 at 50 months)Repeat Tx at 38 months. None. HA at 50 months.CP shunt; cystectomy.L parietal
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American Journal of Neuroradiology: 26 (5)
American Journal of Neuroradiology
Vol. 26, Issue 5
1 May 2005
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Cite this article
Whitney B. Edmister, John I. Lane, Julie R. Gilbertson, Robert D. Brown, Bruce E. Pollock
Tumefactive Cysts: A Delayed Complication following Radiosurgery for Cerebral Arterial Venous Malformations
American Journal of Neuroradiology May 2005, 26 (5) 1152-1157;

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Tumefactive Cysts: A Delayed Complication following Radiosurgery for Cerebral Arterial Venous Malformations
Whitney B. Edmister, John I. Lane, Julie R. Gilbertson, Robert D. Brown, Bruce E. Pollock
American Journal of Neuroradiology May 2005, 26 (5) 1152-1157;
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