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Research ArticleBrain

Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery MR Imaging of Intracranial Metastases

Nil Ercan, Serap Gultekin, Halil Celik, Turgut E. Tali, Yusuf A. Oner and Gonca Erbas
American Journal of Neuroradiology May 2004, 25 (5) 761-765;
Nil Ercan
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Serap Gultekin
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Halil Celik
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Turgut E. Tali
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Yusuf A. Oner
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Gonca Erbas
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  • Fig 1.
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    Fig 1.

    Images obtained in a 57-year-old-man with small-cell lung cancer reveal multiple, enhancing, solid and cystic parenchymal metastases. The number, conspicuity, and contrast enhancement are superior on the postcontrast FLAIR image compared with the postcontrast T1W image. In this patient, FLAIR was performed as the second postcontrast sequence.

    A, Contrast-enhanced T1W image.

    B, Nonenhanced FLAIR image.

    C, Contrast-enhanced FLAIR image.

  • Fig 2.
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    Fig 2.

    Images obtained in a 45-year-old-woman with breast cancer. The conspicuity, extension, and contrast enhancement of the lesions are superior on the postcontrast FLAIR image (C) than on the postcontrast T1W image (A). The leptomeningeal enhancement of frontal lobes (white arrow) is not conspicuous in A as compared with C. For this patient, T1W imaging was performed as the second postcontrast sequence.

    A, Contrast-enhanced T1W image shows abnormal enhancement in the basal cisterns (arrow) and leptomeninges consistent with metastases.

    B, Nonenhanced FLAIR image.

    C, Contrast-enhanced FLAIR image also shows the abnormal enhancement of the leptomeninges (white arrow) and basal cisterns (black arrow).

  • Fig 3.
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    Fig 3.

    Images obtained in a 54-year-old-man with small-cell lung cancer. In this patient, FLAIR imaging was the second postcontrast sequence.

    A and B, Nonenhanced (A) and contrast-enhanced (B) FLAIR images show involvement of the prechiasmal portion of the right optic nerve (white arrow) and extension to the optic chiasm (black arrow) and right optic tract (arrowhead). These findings appear as abnormal hyperintensity in A and as abnormal contrast enhancement in B.

    C, Contrast-enhanced T1W image. Although involvement of optic chiasm is shown as abnormal contrast enhancement (arrow), involvement of the right optic nerve and right optic tract could not be detected.

Tables

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    TABLE 1:

    Distribution of intracranial metastases

    LocalizationNo. of Patients
    Isolated parenchymal metastases24
    Parenchymal and cranial-nerve metastases4
    Parenchymal and leptomeningeal-cisternal metastases5
    Isolated leptomeningeal-cisternal metastases6
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    TABLE 2:

    Evaluation of parenchymal metastases on contrast-enhanced images

    FeatureNo. of Patients
    FLAIR Superior to T1W*FLAIR Equal to T1WFLAIR Inferior to T1W
    Number of lesions520†8‡
    Lesion conspicuity51*27§
    Degree of contrast enhancement55*23‖
    • * In all patients, FLAIR was the second postcontrast sequence.

    • † In 19 patients, FLAIR was the second postcontrast sequence, and in one, the T1W sequence was second.

    • ‡ In four patients, FLAIR was the second postcontrast sequence, and in the other four patients, the T1W sequence was second.

    • § In 18 patients, FLAIR was the second postcontrast sequence, and in nine, the T1W sequence was second.

    • ‖ In 10 patients, FLAIR was the second postcontrast sequence, and in 13, the T1W sequence was second.

    • View popup
    TABLE 3:

    Evaluation of leptomeningeal-cisternal metastases on contrast-enhanced images

    FeatureNo. of Patients
    FLAIR Superior to T1W*FLAIR Equal to T1WFLAIR Inferior to T1W
    Lesion extension8*3†0
    Lesion conspicuity8*03†
    Degree of contrast enhancement8*03†
    • * In five patients, FLAIR was the second postcontrast sequence, and in three, the T1W sequence was second.

    • † In two patients, FLAIR was the second postcontrast sequence, and in one, the T1W sequence was second.

    • View popup
    TABLE 4:

    Evaluation of cranial nerve metastases on contrast-enhanced images

    Patient and InvolvementFLAIRT1W
    Patient 1*
     Right optic nervePositiveNegative
     Optic chiasmPositivePositive
     Right optic tractPositiveNegative
    Patient 2†
     Right optic tractPositiveNegative
    Patient 3*
     Optic chiasmPositiveNegative
     Left optic tractPositiveNegative
    Patient 4†
     Bilateral CNs VII, VIIIPositivePositive
    • * FLAIR was the second postcontrast sequence.

    • † T1W imaging was the second postcontrast sequence.

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American Journal of Neuroradiology: 25 (5)
American Journal of Neuroradiology
Vol. 25, Issue 5
1 May 2004
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Cite this article
Nil Ercan, Serap Gultekin, Halil Celik, Turgut E. Tali, Yusuf A. Oner, Gonca Erbas
Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery MR Imaging of Intracranial Metastases
American Journal of Neuroradiology May 2004, 25 (5) 761-765;

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Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery MR Imaging of Intracranial Metastases
Nil Ercan, Serap Gultekin, Halil Celik, Turgut E. Tali, Yusuf A. Oner, Gonca Erbas
American Journal of Neuroradiology May 2004, 25 (5) 761-765;
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