Article Figures & Data
Figures
- Fig 1.
Methods of rCBF assessment.
Top, 3D images were made by reconstructing the transaxial SPECT data.
Middle, The surface threshold value was set at 30 mL/100 g/min, and the image defects, which indicate the region with rCBF less than 30 mL/100 g/min, were outlined and calculated by using the image-analysis system (arrows).
Bottom, Transaxial images were obtained with the IMP-ARG method. ROIs of 30 × 15 mm were set in the lesion with decreased CBF along the cerebral cortex (arrows), and its value was measured.
- Fig 2.
Characteristic findings in cases with DIND.
Top, Image shows widely decreased cortical rCBF at the left MCA region (arrows).
Bottom, Image shows widely decreased cortical rCBF at the left ACA region (arrows).
- Fig 3.
CBF data in all cases compared according to the type of angiographic vasospasm.
Top, rCBF in the ROI on 2D images.
Middle, Mean hemispheric CBF calculated by using 2D images.
Bottom, The area of decreased cortical rCBF measured on 3D images.
- Fig 4.
Serial changes in cortical rCBF in a case with DIND.
Top left, Six days after the onset of SAH, 3D images show multiple, patchy areas of decreased cortical rCBF.
Top right, cerebral angiography performed on the same day reveals no angiographic vasospasm.
Bottom left, Ten days after the onset of SAH, 3D images show the widely decreased cortical rCBF.
Bottom right, Diffuse angiographic vasospasm is seen on an cerebral angiogram obtained on the same day.
Tables
Parameter Cases without DIND (n = 43) Cases with DIND (n = 15) Mean age ± SD, y 56.8 ± 10.5 54.2 ± 11.6 Sex ratio (male/female) 14/29 4/11 Site of aneurysms* ICA 14 (33) 6 (40) MCA 13 (30) 5 (33) ACA and ACoA 16 (37) 4 (27) Hunt and Hess grade* 1 and 2 22 (51) 7 (47) 3 18 (35) 5 (33) 4 and 5 3 (7) 3 (20) Fisher classification of SAH on CT scans* Group 2 11 (26) 2 (13) Group 3 32 (74) 13 (87) * Data in parentheses are percentages.
Measure rCBF in ROI on 2D Displays, mL/100g/min Mean Hemispheric CBF on 2D Displays, mL/100g/min Area of Decreased Cortical CBF on 3D Displays, cm2 Cases* With DIND (n = 15) 25.0 ± 5.1† 35.5 ± 5.5 22.6 ± 10.0† Without DIND (n = 43) 37.0 ± 4.8 38.0 ± 5.3 7.4 ± 6.6 Size of infarction‡ Large (n = 5) 21.8 ± 4.3 32.6 ± 3.8 32.3 ± 6.6§ Small (n = 10) 26.6 ± 4.6 36.9 ± 5.8 17.8 ± 7.5 Prognosis at 3 mo‡ Poor (n = 6) 22.2 ± 4.2 33.7 ± 4.8 29.8 ± 7.9‖ Fair (n = 9) 26.9 ± 4.5 36.7 ± 5.8 17.8 ± 8.4 * The CBF data obtained at the onset of DIND in the 15 DIND cases were compared with the data on routine studies in the 43 cases without DIND.
† P < .001 compared with cases without DIND.
‡ The CBF data obtained at the onset of DIND in the 15 DIND cases were compared.
§ P = .006 compared with small size of infarction.
‖ P = .043 compared with fair prognosis.
