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Research ArticleNeurointervention

Three-dimensional Time-of-Flight MR Angiography in the Evaluation of Intracranial Aneurysms Treated with Guglielmi Detachable Coils

Nicoletta Anzalone, Claudio Righi, Franco Simionato, Francesco Scomazzoni, Gilberto Pagani, Giliola Calori, Paolo Santino and Giuseppe Scotti
American Journal of Neuroradiology April 2000, 21 (4) 746-752;
Nicoletta Anzalone
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Claudio Righi
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Franco Simionato
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Francesco Scomazzoni
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Gilberto Pagani
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Giliola Calori
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Paolo Santino
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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Giuseppe Scotti
aFrom the Department of Neuroradiology (N.A., C.R., F.Si., F.Sc, G.P., G.S.) and the Epidemiology Unit (G.C.), Scientific Institute H San Raffaele, Milan, Italy; and Varian, Spa (P.S.).
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  • fig 1.
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    fig 1.

    Small anterior communicating artery aneurysm treated with GDCs. The presence of an artifact does not permit evaluation of the aneurysm neck.

    A, 3D-TOF MR angiographic source image (39/6.2/1) shows a region of absence of signal related to the presence of coils in the site of the treated aneurysm. The A2 segment of both anterior cerebral arteries is not visible.

    B, Corresponding targeted MIP reconstruction shows the gap in vascular signal at the site of the treated aneurysm and at the level of the origin of both A2 segments.

    C, Targeted MIP reconstruction from the ultrashort-TE MR angiographic sequence (5/2.1/1) shows the origin of both A2 segments, although the anterior communicating artery is still not visible.

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    fig 2.

    Small basilar tip aneurysm found to be incompletely occluded at MR angiography and completely occluded at DSA follow-up after treatment with GDCs.

    A, DSA study before treatment shows the presence of a small basilar tip aneurysm.

    B, The aneurysm was judged to be completely occluded at the first follow-up DSA study.

    C, On the first follow-up 3D-TOF MR angiogram (39/6.2/1), a small residual patency was detected.

    D, Residual patency of the aneurysm was confirmed at the second DSA follow-up (6 months after the first follow-up study).

  • fig 3.
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    fig 3.

    Small basilar trunk aneurysm incompletely occluded after treatment with GDCs, as demonstrated at the first follow-up examination. The patient was retreated, with complete occlusion of the aneurysm noted at 1-year follow-up study.

    A, DSA shows the presence of residual patency of the treated aneurysm near the neck.

    B, 3D-TOF MR angiogram (43/8/1) shows residual patency with the same extent as seen at DSA, despite the presence of a vascular signal gap, related to the coils, at the P1 segment of the left posterior cerebral artery.

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    fig 4.

    Giant middle cerebral artery bifurcation aneurysm partially treated with incomplete occlusion verified at the 6-month follow-up examination.

    A, MIP reconstruction from basal 3D-TOF MR angiogram (43/8/1) shows flow within the portion of the aneurysm seen previously; the slow flow is responsible for low signal of both the aneurysm and the middle cerebral artery branches.

    B, Enhanced 3D-TOF MR angiogram (43/8/1) better depicts the partially occluded aneurysm and the patency of the middle cerebral artery branches.

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    fig 5.

    Small aneurysm at the origin of the left PICA, which was completely occluded after treatment with GDCs.

    A, 3D-TOF MR angiogram (39/6.2/1) targeted MIP reconstruction shows the aneurysm before treatment.

    B, 3D-TOF MR angiogram (39/6.2/1) targeted MIP reconstruction 6 months after treatment shows complete occlusion of the aneurysm and reperfusion of the left PICA.

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  • TABLE 1:
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    TABLE 1:

    Size of the aneurysms

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    TABLE 2:

    Site of the aneurysms

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    TABLE 3:

    Results of group 1 (MR angiography without contrast enhancement)

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    TABLE 4:

    Results of group 2 (MR angiography with contrast material)

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American Journal of Neuroradiology
Vol. 21, Issue 4
1 Apr 2000
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Cite this article
Nicoletta Anzalone, Claudio Righi, Franco Simionato, Francesco Scomazzoni, Gilberto Pagani, Giliola Calori, Paolo Santino, Giuseppe Scotti
Three-dimensional Time-of-Flight MR Angiography in the Evaluation of Intracranial Aneurysms Treated with Guglielmi Detachable Coils
American Journal of Neuroradiology Apr 2000, 21 (4) 746-752;

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Three-dimensional Time-of-Flight MR Angiography in the Evaluation of Intracranial Aneurysms Treated with Guglielmi Detachable Coils
Nicoletta Anzalone, Claudio Righi, Franco Simionato, Francesco Scomazzoni, Gilberto Pagani, Giliola Calori, Paolo Santino, Giuseppe Scotti
American Journal of Neuroradiology Apr 2000, 21 (4) 746-752;
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  • Matrix Detachable Coils for the Endovascular Treatment of Intracranial Aneurysms: Analysis of Early Angiographic and Clinical Outcomes
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