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Research ArticleBrain

Characteristic MR Lesion Pattern and Correlation of T1 and T2 Lesion Volume with Neurologic and Neuropsychological Findings in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)

Tarek A. Yousry, Klaus Seelos, Michael Mayer, Roland Brüning, Ingo Uttner, Martin Dichgans, Sylvia Mammi, Andreas Straube, Norbert Mai and Massimo Filippi
American Journal of Neuroradiology January 1999, 20 (1) 91-100;
Tarek A. Yousry
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Klaus Seelos
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Michael Mayer
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Roland Brüning
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Ingo Uttner
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Martin Dichgans
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Sylvia Mammi
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Andreas Straube
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Norbert Mai
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Massimo Filippi
aFrom the Departments of Neuroradiology (T.A.Y., K.S.), Neurology (M.M., I.U., M.D., A.S., N.M.), and Diagnostic Radiology (R.B.), Klinikum Grosshadern, Ludwig-Maximilian University, Munich, Germany; and the Department of Neurology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy (S.M., M.F.).
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Characteristic MR Lesion Pattern and Correlation of T1 and T2 Lesion Volume with Neurologic and Neuropsychological Findings in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)
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Tarek A. Yousry, Klaus Seelos, Michael Mayer, Roland Brüning, Ingo Uttner, Martin Dichgans, Sylvia Mammi, Andreas Straube, Norbert Mai, Massimo Filippi
Characteristic MR Lesion Pattern and Correlation of T1 and T2 Lesion Volume with Neurologic and Neuropsychological Findings in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)
American Journal of Neuroradiology Jan 1999, 20 (1) 91-100;

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Characteristic MR Lesion Pattern and Correlation of T1 and T2 Lesion Volume with Neurologic and Neuropsychological Findings in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)
Tarek A. Yousry, Klaus Seelos, Michael Mayer, Roland Brüning, Ingo Uttner, Martin Dichgans, Sylvia Mammi, Andreas Straube, Norbert Mai, Massimo Filippi
American Journal of Neuroradiology Jan 1999, 20 (1) 91-100;
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Cited By...

  • Novel Cysteine-Sparing Hypomorphic NOTCH3 A1604T Mutation Observed in a Family With Migraine and White Matter Lesions
  • Decreased T1 Contrast between Gray Matter and Normal-Appearing White Matter in CADASIL
  • Lacunar Infarcts Are the Main Correlate With Cognitive Dysfunction in CADASIL
  • Positron Emission Tomography Examination of Cerebral Blood Flow and Glucose Metabolism in Young CADASIL Patients
  • Monitoring Disease Progression in CADASIL With Diffusion Magnetic Resonance Imaging: A Study With Whole Brain Histogram Analysis
  • Prolonged Cerebral Transit Time in CADASIL: A Transcranial Ultrasound Study
  • Cerebral Microbleeds in CADASIL: A Gradient-Echo Magnetic Resonance Imaging and Autopsy Study
  • Diffusion Tensor Imaging Study of Subcortical Gray Matter in CADASIL
  • Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy: Decrease in Regional Cerebral Blood Volume in Hyperintense Subcortical Lesions Inversely Correlates with Disability and Cognitive Performance
  • MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL
  • Correlations Between Clinical Findings and Magnetization Transfer Imaging Metrics of Tissue Damage in Individuals With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
  • Clinical Severity in CADASIL Related to Ultrastructural Damage in White Matter : In Vivo Study With Diffusion Tensor MRI
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