- Glial Fibrillary Acidic Protein Astrocytopathy: Review of Pathogenesis, Imaging Features, and Radiographic Mimics
Glial fibrillary acidic protein (GFAP) astrocytopathy is a CNS autoimmune inflammatory disorder characterized by specific antibodies targeting the intracellular filament protein in mature astrocytes. Neuroimaging findings include linear perivascular enhancement in the white matter extending in a radial pattern, periependymal enhancement, longitudinally extensive cord signal changes, intramedullary enhancement, optic neuritis, and papillitis.
- An Optimized CT Protocol for Detecting Suspected Cauda Equina Syndrome: A Comparative Analysis with MRI
This study prospectively evaluated the diagnostic accuracy of an optimized CT lumbar spine protocol as a potential alternative to MRI in assessing suspected neural compression. CT accurately identified all cases requiring urgent decompression. CT had 97% sensitivity, specificity, and positive and negative predictive values in detecting disc pathology in patients presenting with symptoms suggestive of acute neural compression compared with MRI.
- Risk of Hemorrhagic Transformation after Mechanical Thrombectomy without versus with IV Thrombolysis for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of Randomized Clinical Trials
This systematic review and meta-analysis evaluated the risk of intracerebral hemorrhage, and its subtypes associated with mechanical thrombectomy with or without IV thrombolysis for the treatment of acute ischemic stroke due to large-vessel occlusion. The analysis showed that the overall risk of symptomatic intracerebral hemorrhage was comparable between mechanical thrombectomy with IV thrombolysis and mechanical thrombectomy alone.
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