Abstract
SUMMARY: Spinal cord lesions have a real diagnostic and prognostic role in multiple sclerosis. Thus, optimizing their detection on MR imaging has become a central issue with direct therapeutic impact. In this study, we compared the 3D-MP2RAGE sequence with the conventional Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) set for cervical cord lesion detection in 28 patients with multiple sclerosis. 3D-MP2RAGE allowed better detection of cervical lesions (+62%) in this population, with better confidence, due to optimized contrast and high spatial resolution.
ABBREVIATION:
- MAGNIMS
- Magnetic Resonance Imaging in Multiple Sclerosis
Footnotes
This work was performed in a laboratory member of the France Life Imaging network (grant ANR-11-INBS-0006) and was supported by the Fondation pour l’Aide à la Recherche sur la Sclérose en Plaques and Centre National de la Recherche Scientifique.
Disclosures: Sarah Demortière—RELATED: Grant: France Life Imaging Network.* Jean Pelletier—UNRELATED: Board Membership: Roche, Merck, Biogen, Novartis*; Consultancy: Roche, Merck, Biogen, Novartis*; Grants/Grants Pending: Fondation pour l’Aide à la recherche sur la Sclérose en Plaques Roche, Merck*; Payment for Lectures Including Service on Speakers Bureaus: Novartis, Biogen, Roche, Merck.* Virginie Callot—RELATED: Grant: Accueil–Fondation Sclérose en plaques, Comments: grant support for MRI exams. *Money paid to the institution.
Paper previously presented, in part, at: Annual Meeting of the European Research Committee for Treatment and Research in Multiple Sclerosis, October 18–22; 2019; Berlin, Germany (poster p1265), for which S. Demortière held a European Research Committee for Treatment and Research in Multiple Sclerosis fellowship grant.
- © 2020 by American Journal of Neuroradiology
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