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Review ArticleSpine Imaging and Spine Image-Guided Interventions
Open Access

Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?

R.V. Chandra, J. Maingard, H. Asadi, L.-A. Slater, T.-L. Mazwi, S. Marcia, J. Barr and J.A. Hirsch
American Journal of Neuroradiology May 2018, 39 (5) 798-806; DOI: https://doi.org/10.3174/ajnr.A5458
R.V. Chandra
aFrom the Interventional Neuroradiology Unit (R.V.C., H.A., L.-A.S.), Monash Imaging, Monash Health, Melbourne, Victoria, Australia
bFaculty of Medicine, Nursing and Health Sciences (R.V.C., L.-A.S.), Monash University, Melbourne, Victoria, Australia
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J. Maingard
cInterventional Neuroradiology Service (J.M., H.A.), Department of Radiology, Austin Hospital, Melbourne, Victoria, Australia
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H. Asadi
aFrom the Interventional Neuroradiology Unit (R.V.C., H.A., L.-A.S.), Monash Imaging, Monash Health, Melbourne, Victoria, Australia
cInterventional Neuroradiology Service (J.M., H.A.), Department of Radiology, Austin Hospital, Melbourne, Victoria, Australia
dSchool of Medicine, Faculty of Health (H.A.), Deakin University, Waurn Ponds, Victoria, Australia
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L.-A. Slater
aFrom the Interventional Neuroradiology Unit (R.V.C., H.A., L.-A.S.), Monash Imaging, Monash Health, Melbourne, Victoria, Australia
bFaculty of Medicine, Nursing and Health Sciences (R.V.C., L.-A.S.), Monash University, Melbourne, Victoria, Australia
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T.-L. Mazwi
eNeuroendovascular Program (T.-L.M., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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S. Marcia
fDepartment of Radiology (S.M.), SS. Trinità Hospital, Cagliari, Italy
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J. Barr
gInterventional Neuroradiology (J.B.), University of Texas Southwestern Medical Center, Dallas, Texas.
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J.A. Hirsch
eNeuroendovascular Program (T.-L.M., J.A.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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Abstract

SUMMARY: Osteoporotic vertebral compression fractures frequently result in significant morbidity and health care resource use. For patients with severe and disabling pain, vertebral augmentation (vertebroplasty and kyphoplasty) is often considered. Although vertebroplasty was introduced >30 years ago, there are conflicting opinions regarding the role of these procedures in the treatment of osteoporotic vertebral compression fractures. This review article updates clinicians on the published prospective randomized controlled data, including the most recent positive trials that followed initial negative trials in 2009. Analysis of multiple national claim datasets has also provided further insight into the utility of these procedures. Finally, we considered the recent recommendations of national organizations and medical societies that advise on the use of vertebral augmentation procedures for osteoporotic vertebral compression fractures.

ABBREVIATIONS:

NRS
numeric rating scale
PMMA
polymethylmethacrylate
QUALEFFO
Quality of Life Questionnaire of the European Foundation for Osteoporosis
RCT
randomized controlled trial
RDQ
Roland Morris Disability Questionnaire
VAS
Visual Analog Scale
VCF
vertebral compression fracture
  • © 2018 by American Journal of Neuroradiology

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American Journal of Neuroradiology: 39 (5)
American Journal of Neuroradiology
Vol. 39, Issue 5
1 May 2018
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Cite this article
R.V. Chandra, J. Maingard, H. Asadi, L.-A. Slater, T.-L. Mazwi, S. Marcia, J. Barr, J.A. Hirsch
Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?
American Journal of Neuroradiology May 2018, 39 (5) 798-806; DOI: 10.3174/ajnr.A5458

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Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?
R.V. Chandra, J. Maingard, H. Asadi, L.-A. Slater, T.-L. Mazwi, S. Marcia, J. Barr, J.A. Hirsch
American Journal of Neuroradiology May 2018, 39 (5) 798-806; DOI: 10.3174/ajnr.A5458
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Cited By...

  • Clinical Outcomes and Safety Comparison of Vertebroplasty, Balloon Kyphoplasty, and Vertebral Implant for Treatment of Vertebral Compression Fractures
  • ISASS Policy 2018--Vertebral Augmentation: Coverage Indications, Limitations, and/or Medical Necessity
  • Vertebroplasty: Expectation or Evidence-Based Interventional Radiology?
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