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Index by author

March 01, 2018; Volume 39,Issue 3

  1. Pottel, H.

    1. Pediatric Neuroimaging
      Open Access
      Sonographic Development of the Pericallosal Vascularization in the First and Early Second Trimester of Pregnancy
      B. De Keersmaecker, H. Pottel, G. Naulaers and L. De Catte
      American Journal of Neuroradiology March 2018, 39 (3) 589-596; DOI: https://doi.org/10.3174/ajnr.A5562

  2. Poussaint, T.Y.

    1. FELLOWS' JOURNAL CLUBPediatric Neuroimaging
      Multiparametric Analysis of Permeability and ADC Histogram Metrics for Classification of Pediatric Brain Tumors by Tumor Grade
      S. Vajapeyam, D. Brown, P.R. Johnston, K.I. Ricci, M.W. Kieran, H.G.W. Lidov and T.Y. Poussaint
      American Journal of Neuroradiology March 2018, 39 (3) 552-557; DOI: https://doi.org/10.3174/ajnr.A5502

      DTI and dynamic contrast-enhanced MR imaging using T1-mapping with flip angles of 2°, 5°, 10°, and 15°, followed by a 0.1-mmol/kg body weight gadolinium-based bolus was performed on 41 patients in addition to standard MR imaging. Permeability data were processed and transfer constant from the blood plasma into the extracellular extravascular space, rate constant from the extracellular extravascular space back into blood plasma, extracellular extravascular volume fraction, and fractional blood plasma volume were calculated from 3D tumor volumes. Apparent diffusion coefficient histogram metrics were calculated. Wilcoxon tests showed a higher transfer constant from blood plasma into extracellular extravascular space and rate constant from extracellular extravascular space back into blood plasma, and lower extracellular extravascular volume fraction in high-grade tumors. The mean ADCs of FLAIR and enhancing tumor volumes were significantly lower in high-grade tumors. The authors conclude that ADC histogram metrics combined with permeability metrics differentiate low- and high-grade pediatric brain tumors with high accuracy.

  3. Pozzi Mucelli, R.

    1. EDITOR'S CHOICEAdult Brain
      Iodine Extravasation Quantification on Dual-Energy CT of the Brain Performed after Mechanical Thrombectomy for Acute Ischemic Stroke Can Predict Hemorrhagic Complications
      M. Bonatti, F. Lombardo, G.A. Zamboni, F. Vittadello, R. Currò Dossi, B. Bonetti, R. Pozzi Mucelli and G. Bonatti
      American Journal of Neuroradiology March 2018, 39 (3) 441-447; DOI: https://doi.org/10.3174/ajnr.A5513

      Eighty-five consecutive patients who underwent brain dual-energy CT immediately after mechanical thrombectomy for acute ischemic stroke between August 2013 and January 2017 were included. Two radiologists independently evaluated dual-energy CT images for the presence of parenchymal hyperdensity, iodine extravasation, and hemorrhage. Thirteen of 85 patients developed hemorrhage. On postoperative dual-energy CT, parenchymal hyperdensities and iodine extravasation were present in 100% of the patients who developed intracerebral hemorrhage and in 56.3% of the patients who did not. Median maximum iodine concentration was 2.63 mg/mL in the patients who developed intracerebral hemorrhage and 1.4 mg/mL in the patients who did not. The authors conclude that the presence of parenchymal hyperdensity with a maximum iodine concentration of greater than 1.35 mg/mL may identify patients developing intracerebral hemorrhage with 100% sensitivity and 67.6% specificity.

  4. Prasad, R.

    1. EDITOR'S CHOICEAdult Brain
      High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted MR Images: Comparison between Gadobutrol and Linear Gadolinium-Based Contrast Agents
      F.G. Moser, C.T. Watterson, S. Weiss, M. Austin, J. Mirocha, R. Prasad and J. Wang
      American Journal of Neuroradiology March 2018, 39 (3) 421-426; DOI: https://doi.org/10.3174/ajnr.A5538

      This is a retrospective analysis of 59 patients who received only gadobutrol and 60 patients who received only linear gadolinium-based contrast agents. Linear gadolinium-based contrast agents included gadoversetamide, gadobenatedimeglumine, and gadodiamide. T1 signal intensity in the globus pallidus, dentate nucleus, and pons was measured on the precontrast portions of patients' first and seventh brain MRIs. The dentate nucleus/pons signal ratio increased in the linear gadolinium-based contrast agent group while no significant increase was seen in the gadobutrol group. The authors conclude that successive doses of gadobutrol do not result in T1 shortening compared with changes seen in linear gadolinium-based contrast agents.

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