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In this study, arterial spin-labeling perfusion was used as a means to assess the well-known angiogenic activity seen in pituitary macroadenomas. Eleven patients with macroadenoma were studied and their ASL results correlated with histologic total microvascular density. The authors found that routine contrast enhancement did not correlate with microvascular density but CBF did and it also correlated with hypervascularity at surgery or postoperative bleeding in 4 instances.

The current definition of TIA calls for normal imaging including DWI. Here the authors used arterial spin-labeling perfusion to detect abnormalities in nearly 50 patients within 24 hours of symptom onset and in 36 controls. The sensitivity and specificity of ASL in TIA diagnosis was 55.8% and 90.7%, respectively, and in nearly 94% of readings abnormalities that matched the clinical neurologic deficits were identified by the 3 observers. Thus, ASL perfusion is promising in evaluating and understanding TIAs.