Index by author
Royuela, A.
- LetterYou have accessReply:F.M. Kovacs, E. Arana, A. Royuela, A. Estremera, G. Amengual, B. Asenjo, H. Sarasíbar, I. Galarraga, A. Alonso, C. Casillas, A. Muriel, C. Martínez and V. Abraira for the Spanish Back Pain Research NetworkAmerican Journal of Neuroradiology January 2013, 34 (1) E9; DOI: https://doi.org/10.3174/ajnr.A3444
Rubenstein, J.L.
- EDITOR'S CHOICEBrainOpen AccessCombined Diffusion and Perfusion MR Imaging as Biomarkers of Prognosis in Immunocompetent Patients with Primary Central Nervous System LymphomaF.E. Valles, C.L. Perez-Valles, S. Regalado, R.F. Barajas, J.L. Rubenstein and S. ChaAmerican Journal of Neuroradiology January 2013, 34 (1) 35-40; DOI: https://doi.org/10.3174/ajnr.A3165
Here, the authors sought to determine if ADC values and perfusion measurements provided prognostic information in 25 treatment-naïve immunocompetent patients with brain lymphoma. The studied parameters were obtained from the enhancing tumor regions. The results of this investigation reinforce the validity of ADC values as a prognostic biomarker and provide evidence of low tumor CBV as a novel risk factor for adverse prognosis in immunocompetent patients with primary brain lymphoma.
Rusanen, H.
- FELLOWS' JOURNAL CLUBBrainYou have accessLocation of the Clot and Outcome of Perfusion Defects in Acute Anterior Circulation Stroke Treated with Intravenous ThrombolysisN. Sillanpää, J.T. Saarinen, H. Rusanen, I. Elovaara, P. Dastidar and S. SoimakallioAmerican Journal of Neuroradiology January 2013, 34 (1) 100-106; DOI: https://doi.org/10.3174/ajnr.A3149
These investigators studied the impact of clot location in patients with acute stroke receiving IV thrombolysis. Four locations (ICA, proximal M1, distal M1, and M2 segment and more distal) of clots were correlated with CT perfusion maps, mismatches, salvaged brain volumes, and outcomes in 105 patients. Clots that were more proximal in location produced larger perfusion defects and lesion volumes. The amount of tissue salvaged was greater in patients with more distally located clots. In conclusion, admission CBV defects were larger in proximal vessel occlusions. More of the penumbra was salvaged if the occlusion was located more distally. This effect reached a plateau in the distal M1 segment of the MCA.