June 2014
A 71-year-old man presenting with 10-day history of headache, nausea, and vomiting. No significant past medical history or surgical history.
Solitary Fibrous Tumor
- Benign mesenchymal tumor, most often described in the thorax (pleural-based)
- Intracranial solitary fibrous tumors are meningeal-based.
- Clinical Presentation: Nonspecific headache is the most common symptom.
- Key Diagnostic Features: Hyperdense enhancing extra-axial mass lesion. The mass lesion is isointense to the gray matter on T1WI and demonstrates heterogeneous appearance (low and high signal intensity) on T2WI. This heterogeneous appearance has been described as the “yin-yang sign”.
- Morphological and histological characteristics: Increased cellularity, minimal vascularity, and fibrous stroma. Positive CD34, CD99, BCL 2, and vimentin stains.
- DDx: Meningioma, hemangiopericytoma, metastasis, lymphoma
- Rx: Surgical resection
