- Utility of Gadolinium-Based Contrast in Initial Evaluation of Seizures in Children Presenting Emergently
The authors aimed to assess the utility of gadolinium-based contrast agents in MR imaging performed for the evaluation of acute pediatric seizure presentation. In their study population, epileptogenic findings were found in 28% of patients, but gadolinium contrast was found to be of limited additive benefit in these patients.
- Brain Maturation Patterns on Normalized FLAIR MR Imaging in Children and Adolescents
Studies to date have shown signal maturation patterns in the pediatric population using various sequences. However, there is a paucity of information about brain maturation patterns of FLAIR signal intensities across the pediatric range. Additionally, intensities vary widely across FLAIR MR imaging scanners. A FLAIR intensity standardization algorithm would be helpful to normalize intensity across large data sets, allowing comparison of FLAIR intensity in different regions and individuals.
- T2-FLAIR Mismatch Sign in Pediatric Low-Grade Glioma
The T2-FLAIR mismatch sign was not observed in pediatric low-grade gliomas with the common molecular alterations BRAF p.V600E–mutated and KIAA1549-BRAF fused, while it was encountered in low-grade gliomas with rare pediatric molecular alterations.
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