Table 3:

Diagnostic performance of individual MR imaging findings for the diagnosis of meningitisa

MR Imaging FindingsSensitivitySpecificityPPVNPVAccuracy
Leptomeningeal enhancement73.3% (62.6%–82.2%)78.1% (78.1%–99.9%)98.4% (90.2%–99.7%)48.9% (40.0%–57.8%)78.0% (69.0%–85.4%)
Ventriculitis13.8% (7.3%–22.9%)100% (84.6%–100%)100% (100%)22.7% (21.2%–24.2%)31.2% (22.7%–40.8%)
Cerebritis28.7% (19.5%–39.4%)100% (84.6%–100%)100% (100%)26.2% (23.7%–28.9%)43.1% (33.7%–53.0%)
Infarct43.7% (33.1%–54.7%)100% (84.6%–100%)100% (100%)31.0% (27.2%–35.1%)55.1% (45.2%–64.6%)
Extra-axial purulent material32.6% (22.8%–43.5%)95.7% (78.1%–99.9%)96.6% (80.1%–99.5%)27.5% (24.2%–31.0%)36.3% (36.3%–55.7%)
Intraventricular purulent material13.8% (7.3%–22.9%)100% (84.6%–100%)100% (100%)22.7% (21.2%–24.2%)31.2% (22.7%–40.8%)
Abscess/granuloma2.3% (0.28%–8.1%)100% (84.6%–100%)100% (100%)20.6% (20.0%–21.1%)22.0% (14.7%–31.0%)
  • a Numbers in parentheses are 95% confidence intervals. Data were obtained from brain MRIs within 7 days of presentation.