Table 3:

Comparison of ADC histograms in HPV+ versus HPV– OPSCC for each b-value combination^{^a}

	HPV– OPSCC	HPV+ OPSCC	P Value^{^b}
ADC Mean^{^c}
ADC_b0–1000	1117 (SD, 151)	977 (SD, 183)	.038
ADC_{b0–50–100–1000}	1029 (SD, 176)	924 (SD, 185)	.164
ADC_{b0–50–100–750–1000}	1051 (SD, 168)	925 (SD, 176)	.077
ADC_{b0–50–100–500–750–1000}	1061 (SD, 167)	935 (SD, 176)	.084
ADC_{b0–750–1000}	1141 (SD, 156)	983 (SD, 177)	.017
ADC_{b0–500–750–1000}	1127 (SD, 156)	970 (SD, 177)	.017
ADC_b100–1000	947 (SD, 245)	875 (SD, 206)	.214
ADC_b500–1000	838 (SD, 255)	758 (SD, 287)	.176
ADC_b750–1000	900 (SD, 360)	942 (SD, 340)	.942
Skewness
ADC_b0–1000	0.156 (SD, 0.453)	0.486 (SD, 0.444)	.031
ADC_{b0–50–100–1000}	0.266 (SD, 0.442)	0.393 (SD, 0.48)	.258
ADC_{b0–50–100–750–1000}	0.331 (SD, 0.526)	0.363 (SD, 0.609)	.445
ADC_{b0–50–100–500–750–1000}	0.31 (SD, 0.542)	0.363 (SD, 0.649)	.383
ADC_{b0–750–1000}	0.177 (SD, 0.518)	0.506 (SD, 0.483)	.046
ADC_{b0–500–750–1000}	0.2 (SD, 0.496)	0.499 (SD, 0.458)	.034
ADC_b100-1000	0.136 (SD, 0.427)	0.069 (SD, 0.486)	.468
ADC_b500–1000	0.229 (SD, 0.431)	0.103 (SD, 0.47)	.537
ADC_b750–1000	0.672 (SD, 0.739)	0.435 (SD, 0.383)	.214
Excess kurtosis
ADC_b0–1000	0.12 (SD, 0.71)	1.22 (SD, 0.45)	< .001
ADC_{b0–50–100–1000}	0.34 (SD, 0.81)	1.36 (SD, 0.69)	< .001
ADC_{b0–50–100–750–1000}	0.57 (SD, 1.25)	1.64 (SD, 1.15)	.008
ADC_{b0–50–100–500–750–1000}	0.55 (SD, 1.25)	1.74 (SD, 1.23)	.007
ADC_{b0–750–1000}	0.21 (SD, 0.81)	1.22 (SD, 0.58)	.002
ADC_{b0–500–750–1000}	0.2 (SD, 0.84)	1.19 (SD, 0.53)	.002
ADC_b100–1000	0.51 (SD, 1.2)	1.22 (SD, 1.09)	.019
ADC_b500–1000	0.19 (SD, 0.84)	0.7 (SD, 1.1)	.188
ADC_b750–1000	0.76 (SD, 2.18)	0.3 (SD, 1.09)	.942

↵a Data are means.
↵b Mann-Whitney-Wilcoxon test.
↵c Units in ×10⁻⁶mm²/s.