Patient and tumor characteristics
| HPV– OPSCC (n = 23) | HPV+ OPSCC (n = 11) | P Value | |
|---|---|---|---|
| Average age (range) (yr) | 62 (50–82) | 62 (48–85) | .986a |
| Sex | |||
| Women | 7 (7/23, 30%) | 6 (6/11, 55%) | |
| Men | 16 (16/23, 70%) | 5 (5/11, 45%) | .329b |
| Tumor location | |||
| Oropharynx | 23 (23/23, 100%) | 11 (11/11, 100%) | |
| T classification according to AJCC 20184,5 | .944c | ||
| T1 | 3 (3/23, 13%) | 0 (0/11, 0%) | |
| T2 | 3 (3/23, 13%) | 2 (2/11, 18%) | |
| T3 | 5 (5/23, 22%) | 2 (2/11, 18%) | |
| T4 | 12 (12/23, 52%) | 7 (7/11, 64%) | |
| N classification according to AJCC 20184,5 | .138c | ||
| N0 | 5 (5/23, 22%) | 0 (0/11, 0%) | |
| N1 | 3 (3/23, 13%) | 5 (5/11, 45%) | |
| N2 | 15 (15/23, 65%) | 6 (6/11, 55%) | |
| N3 | 0 (0/23, 0%) | 0 (0/11, 0%) | |
| M classification according to AJCC 20184,5 | .630c | ||
| M0 | 22 (22/23, 96%) | 11 (11/11, 100%) | |
| M1 | 1 (1/23, 4%) | 0 (0/11, 0%) | |
| Tumor keratinization at histopathology | .140b | ||
| Present | 14 (14/23, 61%) | 7 (7/11, 64%) | |
| Absent | 9 (9/23, 39%) | 4 (4/11, 36%) | |
| Mean proliferation index, MIB-1 (range) (%) | 55 (15–90) | 69 (50–90) | .126d |