Table 1:

Demographic and CSF pressure-volume parameters for patients with clinical and imaging features of SIH, all of whom were suspected of having CVFa

Total (n = 22)Definite or Probable CVF (n = 8)No CVF Identified (n = 14)P Value
Age (yr)57.360.055.8.5
Sex59.1% F37.5% F71.4% F.12
Increase in relative pressure during normal saline infusion (cm H20)146.7% (SD, 17.3%)148.5% (SD, 17.9%)145.4% (SD, 27.0%).93
Total volume infusion (mL)20.7 (SD, 1.8)27.6 (SD, 2.9)15.9 (SD, 4.1)<.001
CSC curves with abrupt pressure loss11/34 (32.4%)4/14 (28.6%)7/20 (35.0%).69
Opening pressure (cm H20)11.6 (SD, 3.8)9.8 (SD, 0.9)12.8 (SD, 0.8).02
PVIb (mL H20)63.9 (SD, 7.5)77.5 (SD, 10.3)54.3 (SD, 10.1).13
Copc (mL/cm H20)2.6 (SD, 0.3) mL/cm H203.8 (SD, 0.5) mL/cm H201.8 (SD, 0.3) mL/cm H20<.001
Overall compliance (linear slope of CSC curve) (mL/cm H20)2.0 (SD, 0.3)3.1 (SD, 0.6)1.3 (SD, 0.3).005

  • ↵a Eight patients had definite or probable CVF diagnosed on CTM, and the remaining cases (14/22) remain unconfirmed. All P values represent comparison of diagnosed-versus-undiagnosed groups. Data represent either proportions or mean values with standard deviation (SD).

  • ↵b Equation 1.

  • ↵c Equation 2.