Baseline patient and tumor characteristics
| Total (n = 59) | HPV+ (n = 28) | HPV– (n = 31) | P Value | |
|---|---|---|---|---|
| Age (yr) | 66.3 | 66.2 | 67.4 | .9 |
| Sex | ||||
| Male | 43 | 19 | 24 | .41 |
| Female | 16 | 9 | 7 | |
| Smoker | 34/59 | 8/28 | 26/31 | <.0001 |
| Site | 38, Palatine tonsil | 20, Palatine tonsil | 18, Palatine tonsil | .61 |
| 17, Tongue base | 7, Tongue base | 10, Tongue base | ||
| 3, Soft palate | 1, Soft palate | 2, Soft palate | ||
| 1, Posterior wall | 1, Posterior wall | |||
| TNM classification | ||||
| T | T2 = 25 | T2 = 16 | T2 = 9 | .08 |
| T3 = 2 | T3 = 1 | T3 = 1 | ||
| T4 = 32 | T4 = 11 | T4 = 21 (16, T4a; 5, T4b) | ||
| N | N0 = 14 | N0 = 7 | N0 = 7 | .002 |
| N1 = 15 | N1 = 13 | N1 = 2 | ||
| N2 = 18 | N2 = 6 | N2 = 12 (8, N2b; 4, N2c) | ||
| N3 = 12 | N3 = 2 | N3 = 10 (N3b = 10) | ||
| M | M0 = 57 | M0 = 27 | M0 = 30 | .14 |
| M1 = 2 | M1 = 1 | M1 = 1 |
Note:—HPV+ indicates human papillomavirus–positive; HPV–, human papillomavirus–negative.