Demographic, clinical, and QSM-related characteristics of the patient population
RRMS | SPMS | Whole Group | |
---|---|---|---|
No. | 21 | 15 | 36 |
Age (yr) | 36.2 ± 5.8 | 49.5 ± 9.2 | 40.5 ± 8.0 |
Disease duration (yr) | 9.7 ± 6.3 | 16.9 ± 7.0 | 12.7 ± 7.5 |
Sex (F/M) | 16:5 | 9:6 | 25:11 |
EDSS (mean) (range) | 2.0 (1.0–5.5) | 5.0 (4.0–7.0) | 3.0 (1.0–7.0) |
No. of intracortical lesions (mean) | |||
Total | 4.5 ± 3.6 | 2.1 ± 2.6 | 3.5 ± 3.4 |
QSM-hyperintense | 2.8 ± 2.3 | 0.9 ± 1.2 | 2.0 ± 2.1 |
QSM-isointense | 0.6 ± 0.7 | 0.1 ± 0.4 | 0.4 ± 0.6 |
QSM-hypointense | 1.1 ± 1.5 | 0.9 ± 1.8 | 1.0 ± 1.6 |
No. of leukocortical lesions (mean) | |||
Total | 2.6 ± 3.1 | 5.0 ± 3.5 | 3.6 ± 3.5 |
QSM-hyperintense | 1.5 ± 1.8 | 1.9 ± 1.5 | 1.7 ± 1.7 |
QSM-isointense | 0.5 ± 0.9 | 0.6 ± 1.3 | 0.5 ± 1.1 |
QSM-hypointense | 0.5 ± 0.9 | 2.4 ± 2.4 | 1.3 ± 1.9 |
No. of total lesions (mean) | |||
Total | 7.1 ± 5.2 | 7.1 ± 5.0 | 7.1 ± 5.1 |
QSM-hyperintense | 4.2 ± 3.4 | 2.8 ± 2.3 | 3.6 ± 3.0 |
QSM-isointense | 1.0 ± 1.2 | 0.7 ± 1.3 | 0.9 ± 1.3 |
QSM-hypointense | 1.6 ± 1.8 | 3.3 ± 3.7 | 2.3 ± 2.8 |