Table 3:

Comparison of intracranial injuries seen on MRI by type of ECMOa

MRI FindingsTotal (n = 81)VA ECMO (n = 67)VV ECMO (n = 14)P Valueb
Any injury (hemorrhage, infarction, volume loss, increased subarachnoid spaces)37 (46)33 (49)4 (29).157
Any hemorrhage19 (23)15 (22)4 (26).247
Major hemorrhage3 (4)3 (4)0 (0).420
Minor hemorrhage16 (20)12 (18)4 (29).362
Any infarction18 (22)16 (24)2 (14).432
Major infarction (total including arterial,c venous infarcts, and others)8 (10)8 (12)0 (0).173
Arterial: ACA territory4 (5)4 (6)0 (0).879
Arterial: MCA territory4 (5)4 (6)0 (0).879
Arterial: PCA territory1 (1)1 (1)0 (0).646
Minor infarctions (total)10 (13)8 (12)2 (14).808
Cerebellar injury5 (6)5 (7)0 (0).291
Volume loss
    Any28 (35)25 (37)3 (21).256
    Cortical5 (6)5 (7)0 (0).291
    White matter27 (33)24 (36)3 (21).299
    Deep gray nuclei3 (4)3 (4)0 (0).420
    Cerebellum3 (4)3 (4)0 (0).420
    Brain stem3 (4)3 (4)0 (0).420
Ventricular size
    Normal60 (74)49 (73)11 (79).673
    Slit2 (3)2 (3)0 (0).513
    Mild ventriculomegaly14 (17)11 (16)3 (21).652
    Moderate ventriculomegaly4 (5)4 (6)0 (0).879
    Severe ventriculomegaly1 (1)1 (1)0 (0).646
    Increased subarachnoid spaces36 (44)34 (51)2 (14).012
  • a Data presented as no. of patients (%).

  • b Comparison between VA and VV.

  • c There was overlap among arterial territories on some studies.