Table 4:

RCI (mean) of patients on natalizumab and IFNb/GA between baseline and month 12

RCI Baseline–Month 12Patients on NatalizumabPatients on IFNb/GAP Value
Symbol Digit Modalities Test−0.02 ± 0.68−0.04 ± 0.77.993
SPART-total0.18 ± 1.46−0.49 ± 1.42.432
SPART-delayed0.54 ± 1.690.06 ± 1.99.629
VLGT–immediate recall−0.67 ± 0.880.20 ± 1.03.024a
VLGT–short-term free recall−0.15 ± 1.010.06 ± 0.75.575
VLGT–long-term free recall−0.21 ± 1.360.47 ± 0.84.211
WLG–Animals0.15 ± 0.90−0.40 ± 0.81.185
WLG–Professions−0.19 ± 0.880.04 ± 1.17.835
WLG–4 letter “M” words−0.61 ± 0.88−0.36 ± 1.08.129
Digit Span Forward−0.01 ± 0.870.06 ± 0.85.842
Digit Span Backward−0.31 ± 0.89−0.34 ± 1.42.572
TMT–Letter-Number Switching0.41 ± 3.230.59 ± 2.91.922
Stroop-interference−1.00 ± 2.14−0.78 ± 1.63.595
  • Note:—SPART indicates Spatial Recall Task; VLGT, Verbal Memory and Learning Task; WLG, Word List Generation; TMT, Trail-Making Test.

  • a A significant difference between the patient groups.